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Santiago J. Martinez

Researcher at Cedars-Sinai Medical Center

Publications -  7
Citations -  29

Santiago J. Martinez is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Trypanosoma cruzi & Chagas disease. The author has an hindex of 1, co-authored 3 publications receiving 9 citations. Previous affiliations of Santiago J. Martinez include National University of Cuyo.

Papers
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Journal ArticleDOI

Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy.

Santiago J. Martinez, +5 more
- 08 May 2020 - 
TL;DR: The current state of T. cruzi infection and prognosis is discussed and it is looked forward to the day when it will be possible to employ precision health to predict disease outcome and determine whether and when treatment of infection may be necessary.
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Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival.

Cynthia Vanesa Rivero, +13 more
- 01 Jan 2021 - 
TL;DR: In this article, a repurposed drug, carvedilol, was used to increase the accumulation of immature autophagosomes characterized by lower acidity and hydrolytic properties.
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Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection.

Xiaomo Li, +11 more
- 10 May 2021 - 
TL;DR: In this paper, a vesicular nanocarrier formulation was proposed for the treatment of T. cruzi infection in mice, which was tested in a mouse model of infection with the protozoan parasite.
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Induction of Autophagy by Ursolic Acid Promotes the Elimination of Trypanosoma cruzi Amastigotes From Macrophages and Cardiac Cells

M. Cristina Vanrell, +5 more
- 08 Jul 2022 - 
TL;DR: The aim of this work was to study the effect of UA on T. cruzi infection in vitro in the late infection stage, when the nests of intracellular parasites are forming, in both macrophages and cardiac cells and to point to UA as an interesting lead for Chagas disease treatment in the future.
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Biological Features of Tcm: A New Trypanosoma Cruzi Isolate from Argentina (Dtu V) Displaying Slow Growth, Cardiac Tropism, and Susceptibility to Benznidazole

Patricia Silvia Romano, +5 more
- 01 Jan 2022 -