S
Sara G. Grossi
Researcher at University at Buffalo
Publications - 60
Citations - 10292
Sara G. Grossi is an academic researcher from University at Buffalo. The author has contributed to research in topics: Clinical attachment loss & Periodontitis. The author has an hindex of 41, co-authored 60 publications receiving 9782 citations. Previous affiliations of Sara G. Grossi include East Carolina University & State University of New York System.
Papers
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Journal ArticleDOI
Assessment of risk for periodontal disease. I. Risk indicators for attachment loss.
Sara G. Grossi,Joseph J. Zambon,Alex W. Ho,Gary G. Koch,Robert G. Dunford,Eli E. Machtei,Ola M. Norderyd,Robert J. Genco +7 more
TL;DR: Age, smoking, diabetes mellitus, and the presence of subgingival P. gingivalis and B. forsythus are risk indicators for attachment loss, which remain valid after controlling for gender, socioeconomic status, income, education, and oral hygiene status.
Journal ArticleDOI
Periodontal Disease and Diabetes Mellitus: A Two-Way Relationship*
Sara G. Grossi,Robert J. Genco +1 more
TL;DR: It is proposed that an infection-mediated upregulation cycle of cytokine synthesis and secretion by chronic stimulus from lipopolysaccharide and products of periodontopathic organisms may amplify the magnitude of the advanced glycation end product (AGE)-mediated cytokine response operative in diabetes mellitus.
Journal ArticleDOI
Assessment of Risk for Periodontal Disease. II. Risk Indicators for Alveolar Bone Loss
Sara G. Grossi,Robert J. Genco,Eli E. Machtei,Alex W. Ho,Gary G. Koch,Robert G. Dunford,Joseph J. Zambon,Ernest Hausmann +7 more
TL;DR: This study examined the risk indicators for alveolar bone loss associated with periodontal infection and potential explanatory variables including age, gender, history of systemic diseases, smoking, and presence of 8 subgingival bacteria to find factors which were positively associated with more severe bone loss.
Journal ArticleDOI
Periodontal Infections Contribute to Elevated Systemic C-Reactive Protein Level
Barbara Noack,Robert J. Genco,Maurizio Trevisan,Sara G. Grossi,Joseph J. Zambon,Ernesto De Nardin +5 more
TL;DR: The extent of increase in CRP levels in periodontitis patients depends on the severity of the disease after adjusting for age, smoking, body mass index, triglycerides, and cholesterol, which were found to be significant covariates.
Journal ArticleDOI
A Proposed Model Linking Inflammation to Obesity, Diabetes, and Periodontal Infections
TL;DR: Obesity is a significant predictor of periodontal disease and insulin resistance appears to mediate this relationship, and obesity is associated with high plasma levels of TNFα and its soluble receptors, which in turn may lead to a hyperinflammatory state increasing the risk for periodontAL disease and also accounting in part for insulin resistance.