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Satish Kumar

Researcher at Mahatma Gandhi Institute of Medical Sciences

Publications -  47
Citations -  558

Satish Kumar is an academic researcher from Mahatma Gandhi Institute of Medical Sciences. The author has contributed to research in topics: Antigen & Tuberculosis. The author has an hindex of 15, co-authored 47 publications receiving 483 citations.

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Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus.

TL;DR: Observations made in this study may extend an assuring platform for developing anti-viral competitive inhibitors against ZIKV infection.
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Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking

TL;DR: Among 13 natural compounds, theaflavin, found in green tea, was observed to inhibit H1N1 NA proteins strongly supported by lowest docking energy, which may be of interest to consider for further in vitro and in vivo evaluation.
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Computational approach to understanding the mechanism of action of isoniazid, an anti-TB drug.

TL;DR: Docking results revealed the formation of a single hydrogen (H) bond between the secondary amine nitrogen (-NH) of INH with Thr or Asn residues in place of Serine at 315 position of KatG mutant strains respectively, whereas in the case of the wild type, there was no H-bond formation observed, which may prevent free radical formation by KatG in mutant strains thus the development of resistance to the drug.
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Immunodiagnosis of tuberculosis: An update.

TL;DR: There is lack of consistent elevation in all the three Ig classes in active infection thus making it more important to determine the ideal antibody isotype assay for reliable diagnosis of tuberculosis and to save the costs of the patient for unnecessary investigations.
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A cocktail of affinity-purified antibodies reactive with diagnostically useful mycobacterial antigens ES-31, ES-43, and EST-6 for detecting the presence of Mycobacterium tuberculosis

TL;DR: Analysis of different groups of TB sera showed that circulating immune-complexed antigen is a sensitive marker than free antigen, and combinatorial use of antibodies showed improved sensitivity and was thus observed to be better than single antibody.