Simultaneous determination of cholesterol, ascorbic acid and uric acid as three essential biological compounds at a carbon paste electrode modified with copper oxide decorated reduced graphene oxide nanocomposite and ionic liquid

A critical review on the use of potentiometric based biosensors for biomarkers detection

Analysis of food, pharmaceutical, and environmental compounds is an inevitable issue to evaluate quality of the compounds used in human life. Quality of drinking water, food products, and pharmaceutical compounds is directly associated with human health. Presence of forbidden additives in food products, toxic compounds in water samples and drugs with low quality lead to important problems for human health. Therefore, attention to analytical strategy for investigation of quality of food, pharmaceutical, and environmental compounds and monitoring presence of forbidden compounds in materials used by humans has increased in recent years. Analytical methods help to identify and quantify both permissible and unauthorized compounds present in the materials used in human daily life. Among analytical methods, electrochemical methods have been shown to have more advantages compared to other analytical methods due to their portability and low cost. Most of big companies have applied this type of analytical methods because of their fast and selective analysis. Due to simple operation and high diversity of electroanalytical sensors, these types of sensors are expected to be the future generation of analytical systems. Therefore, many scientists and researchers have focused on designing and fabrication of electroanalytical sensors with good selectivity and high sensitivity for different types of compounds such as drugs, food, and environmental pollutants. In this paper, we described the mechanism and different examples of DNA, enzymatic and electro-catalytic methods for electroanalytical determination of drug, food and environmental compounds.

Electrochemical Sensors, a Bright Future in the Fabrication of Portable Kits in Analytical Systems

ZnO-based nanostructured electrodes for electrochemical sensors and biosensors in biomedical applications

This paper reports an electroanalytical sensor developed based on reduced graphene oxide/FeNi3 (FeNi3/rGO)-ionic liquid (n-hexyl-3-methylimidazolium hexafluoro phosphate (HMPF6) carbon paste electrode (CPE) for determining the antioxidant additive tertbutylhydroquinone (TBHQ) in the presence of folic acid. The FeNi3/rGO synthesized by hydrothermal strategy and characterized by X-ray diffraction (XRD) and FESEM methods. The electrochemical response were found to be linearly symmetrical to TBHQ and folic acid concentrations in the range from 0.05 to 900 μM and 0.6–1100 μM with detection limits of 10.0 nM and 0.1 μM, respectively. The FeNi3/rGO/HMPF6/CPE showed high-quality for determination of TBHQ in the presence of folic acid in the real samples with the separation potential ∼600 mV.

3D reduced graphene oxide/FeNi3-ionic liquid nanocomposite modified sensor; an electrical synergic effect for development of tert-butylhydroquinone and folic acid sensor

Simultaneous determination of doxorubicin and dasatinib as two breast anticancer drugs uses an amplified sensor with ionic liquid and ZnO nanoparticle

Epirubicin (EB) and topotecan (TP) are two major anticancer drugs that are used in breast cancer therapy with many side effects In this research, we introduce a carbon paste electrode, modified with 1-butylpyridinium hexafluorophosphate and CuO nanoparticles (CPE/1-BPr/CuO-NPs), as an amplified sensor for the electrochemical determination of EB The electrochemical behavior of EB was initially studied on the surface of CPE/1-BPr/CuO-NPs, CPE/CuO-NPs, CPE/1-BPr, and on bare carbon paste electrodes The CPE/1-BPr/CuO-NPs showed two separate oxidation signals with a potential of 628 mV and 935 mV in the oxidation of EB and TP, respectively; these potentials are sufficient for determining them simultaneously The linear response range was found to be 003 to 800 μM (R2 = 09972) and 07 to 800 μM (R2 = 09984) for the EB and TP concentrations, with limits of detection (LODs) of 0008 μM and 03 μM, respectively Finally, the concentrations of EB and TP were successfully measured by CPE/1-BPr/CuO-NPs as a voltammetric sensor in real samples

An amplified platform nanostructure sensor for the analysis of epirubicin in the presence of topotecan as two important chemotherapy drugs for breast cancer therapy

Seyed A. R. Alavi-Tabari

Papers

Simultaneous determination of doxorubicin and dasatinib as two breast anticancer drugs uses an amplified sensor with ionic liquid and ZnO nanoparticle

An amplified platform nanostructure sensor for the analysis of epirubicin in the presence of topotecan as two important chemotherapy drugs for breast cancer therapy