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Seyed Naser Ostad

Researcher at Tehran University of Medical Sciences

Publications -  22
Citations -  964

Seyed Naser Ostad is an academic researcher from Tehran University of Medical Sciences. The author has contributed to research in topics: Drug carrier & Insulin. The author has an hindex of 14, co-authored 22 publications receiving 807 citations. Previous affiliations of Seyed Naser Ostad include University of Tehran.

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Chitosan–Pluronic nanoparticles as oral delivery of anticancer gemcitabine: preparation and in vitro study

TL;DR: Results suggest that nanoparticles could be considered as an efficient oral formulation for colon cancer treatment and an increase in the cytotoxicity of gemcitabine embedded in the nanoparticles in comparison with drug alone.
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Surface modification of PLGA nanoparticles via human serum albumin conjugation for controlled delivery of docetaxel.

TL;DR: Albumin conjugated PLGA nanoparticles may represent a promising drug delivery system in cancer therapy and results in more cytotoxicity against tumor cell lines compared with free docetaxel and unconjugated PL GA nanoparticles.
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Self assembled hyaluronic acid nanoparticles as a potential carrier for targeting the inflamed intestinal mucosa.

TL;DR: Results revealed the promising potential of HA nanoparticles as a targeted drug delivery system for IBD treatment as budesonide loaded HANPs demonstrated higher anti-inflammatory effect on IL-8 and TNF-α secretion in inflamed cell model compared to the same dose of free drug.
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Mesoporous silica nanoparticles functionalized with folic acid/methionine for active targeted delivery of docetaxel.

TL;DR: Ex vivo fluorescent images of tumor-induced BALB/c mice organs revealed the ability of MSN-FA to reach the tumor tissues and showed the possibility of targeted drug delivery for breast cancer.
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Stimulatory Effects of Malathion on the Key Enzymes Activities of Insulin Secretion in Langerhans Islets, Glutamate Dehydrogenase and Glucokinase

TL;DR: It was concluded that pancreatic islet key enzymes are stimulated following acute and subchronic exposure to malathion though not enough to overcome to hyperglycemia.