S
Sheila Sprague
Researcher at McMaster University
Publications - 273
Citations - 11730
Sheila Sprague is an academic researcher from McMaster University. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 51, co-authored 242 publications receiving 9408 citations. Previous affiliations of Sheila Sprague include James Cook University Hospital & St. Joseph's Healthcare Hamilton.
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Journal ArticleDOI
Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis
Nicole Simunovic,Philip J. Devereaux,Sheila Sprague,Gordon H. Guyatt,Emil H. Schemitsch,Justin DeBeer,Mohit Bhandari +6 more
TL;DR: Earlier surgery was associated with a lower risk of death and lower rates of postoperative pneumonia and pressure sores among elderly patients with hip fracture, suggesting that reducing delays may reduce mortality and complications.
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Internal fixation compared with arthroplasty for displaced fractures of the femoral neck. A meta-analysis.
Mohit Bhandari,Philip J. Devereaux,Marc F. Swiontkowski,Paul Tornetta,William T. Obremskey,Kenneth J. Koval,Sean E. Nork,Sheila Sprague,Emil H. Schemitsch,Gordon H. Guyatt +9 more
TL;DR: In comparison with internal fixation, arthroplasty for the treatment of a displaced femoral neck fracture significantly reduces the risk of revision surgery, at the cost of greater infection rates, blood loss, and operative time and possibly an increase in early mortality rates.
Journal Article
Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials
Mohit Bhandari,Jason W. Busse,Dianne Jackowski,Victor M. Montori,Holger J. Schünemann,Sheila Sprague,Derek Mears,Emil H. Schemitsch,Dianne Heels-Ansdell,Philip J. Devereaux +9 more
TL;DR: Industry-funded trials are more likely to be associated with statistically significant pro-industry findings, both in medical trials and surgical interventions.
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Treatment of acute Achilles tendon ruptures: a systematic overview and metaanalysis.
Mohit Bhandari,Gordon H. Guyatt,Farhan Siddiqui,Farrah Morrow,Jason W. Busse,Ross Leighton,Sheila Sprague,Emil H. Schemitsch +7 more
TL;DR: A quantitative systematic review of randomized and quasirandomized trials was conducted to determine the effect of surgical versus conservative treatment of acute Achilles tendon ruptures on rates of rerupture, with wide confidence intervals around the estimates of risk reduction suggest a large trial is needed to establish risks and benefits.
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A lack of consensus in the assessment of fracture healing among orthopaedic surgeons
Mohit Bhandari,Gordon H. Guyatt,Marc F. Swiontkowski,Paul Tornetta,Sheila Sprague,Emil H. Schemitsch +5 more
TL;DR: There is a lack of consensus in the assessment of fracture healing in tibial shaft fractures among orthopaedic surgeons and Varying definitions of nonunion and malunion may influence the decision to intervene in an effort to promote fracture healing and/or realign the fracture.