S
Shengling Zhang
Researcher at Southwest University
Publications - 3
Citations - 183
Shengling Zhang is an academic researcher from Southwest University. The author has contributed to research in topics: Transcription activator-like effector nuclease & Genome editing. The author has an hindex of 2, co-authored 3 publications receiving 174 citations.
Papers
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Journal ArticleDOI
Highly efficient and specific genome editing in silkworm using custom TALENs.
Sanyuan Ma,Shengling Zhang,Feng Wang,Yong Liu,Yuanyuan Liu,Hanfu Xu,Chun Liu,Ying Lin,Ping Zhao,Qingyou Xia +9 more
TL;DR: It is demonstrated that (i) TALENs can be used in silkworm and (ii) heritable large chromosomal deletions can be induced by two pairs of TALens in whole organisms.
Journal ArticleDOI
Multiplex genomic structure variation mediated by TALEN and ssODN
Sanyuan Ma,Xiaogang Wang,Yuanyuan Liu,Jie Gao,Shengling Zhang,Run Shi,Jiasong Chang,Ping Zhao,Qingyou Xia +8 more
TL;DR: An efficient strategy to induce targeted GSV including chromosomal deletions, duplications and inversions in a precise manner is presented and it is the first time to show that co-introduction of TALEN and ssODN generated unwanted complex structure variation.
Patent
Deleting system for long fragments in genome based on TALEN (transcription activator-like effector Nuclease) and ssODNs (single stranded oligonucleotides) and application thereof
TL;DR: In this article, a deleting system for long fragments in a genome based on TALEN and ssODNs was proposed, which is composed of a transcription activator-like effector nuclease (TALEN) and a single stranded oligonucleotides (ssODNs) of a shearing objective gene target sequence.