Shirin Ghods

TL;DR: The central regulatory role of quorum sensing and signaling systems by nucleotide-based second messengers resulting in different lifestyles of P. aeruginosa is reviewed and various regulatory proteins will be discussed which form a plethora of controlling systems acting at transcriptional level for timely expression of genes enabling rapid responses to external stimuli and unfavorable conditions.

TL;DR: Bacterial two-hybrid assays and pulldown experiments showed that the catalytic subunit Alg8 directly interacts with the proposed copolymerase Alg44 while embedded in the cytoplasmic membrane, providing new insights into the molecular mechanisms of the synthesis of the unique polysaccharide, alginate.

TL;DR: advanced understanding of alginate biosynthesis pathway and involved enzymes creates an opportunity for bioengineering and synthetic biology approaches toward the production ofAlginates exhibiting desired material properties suitable for pharmaceutical and biomedical applications.

TL;DR: The formation, architecture, and composition of P. actinidiae biofilms are studied as a model to assess the efficacies of bactericidal compounds and Experimental evidence that P. syringae pv.

TL;DR: Insight is provided into the c-di-GMP-mediated activation of alginate polymerization while assigning functional roles to Alg8 and Alg44, including their subcellular localization and distribution, which is the hallmark of chronic infections of cystic fibrosis patients.