S
Shiro Yorifuji
Researcher at Osaka University
Publications - 82
Citations - 2270
Shiro Yorifuji is an academic researcher from Osaka University. The author has contributed to research in topics: Transcranial magnetic stimulation & Transthyretin. The author has an hindex of 25, co-authored 82 publications receiving 2119 citations.
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Journal ArticleDOI
Treatment of Kearns‐Sayre syndrome with coenzyme Q10
Saburo Ogasahara,Yoshiro Nishikawa,Shiro Yorifuji,Fumihisa Soga,Yusaku Nakamura,Mitsuo Takahashi,Shigeo Hashimoto,Norio Kono,Seiichiro Tarui +8 more
TL;DR: Although the mitochondrial fraction was increased in muscles from KSS patients, CoQ content was slightly low, and Administration of 120 to 150 mg/d of CoQ improved abnormal metabolism of pyruvate and NADH oxidation in skeletal muscle.
Journal ArticleDOI
Cognitive function in amyotrophic lateral sclerosis
TL;DR: It is believed that inattention and executive dysfunction alternatives may evolve in patients with ALS corresponding to the pathologic process in the frontal lobe resulting in a continuum of cognitive disability ranging from significant impairment to normality.
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Determination of language dominance with synthetic aperture magnetometry: comparison with the Wada test.
Masayuki Hirata,Amami Kato,Masaaki Taniguchi,Youichi Saitoh,Hirotomo Ninomiya,Aya Ihara,Aya Ihara,Haruhiko Kishima,Satoru Oshino,Takahito Baba,Shiro Yorifuji,Toshiki Yoshimine +11 more
TL;DR: Reliability of MEG imaging with SAM is sufficient to evaluate language dominance preoperatively in neurosurgical patients, and lateralization of low gamma band desynchronizations in the IFG or MFG is a good indicator of the side of language dominance.
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Improvement of abnormal pyruvate metabolism and cardiac conduction defect with coenzyme Ql0 in Kearns‐Sayre syndrome
Saburo Ogasahara,Shiro Yorifuji,Yoshiro Nishikawa,Mitsuo Takahashi,Keiji Wada,T. Hazama,Yusaku Nakamura,Shigeo Hashimoto,Norio Kono,Seiichiro Tarui +9 more
TL;DR: Serum levels of lactate and pyruvate became normal, with improvement of atrioventricular block and ocular movements, and coenzyme Ql0 concentration was decreased in serum and in the mitochondrial fraction of skeletal muscle in a patient with Kearns-Sayre syndrome.
Journal ArticleDOI
Long‐term coenzyme Q10 therapy for a mitochondrial encephalomyopathy with cytochrome c oxidase deficiency A 31P NMR study
Yoshiro Nishikawa,M. Takahashi,Shiro Yorifuji,Yusaku Nakamura,S. Ueno,Seiichiro Tarui,T. Kozuka,T. Nishimura +7 more
TL;DR: The results indicate that CoQ has clinical value in the long-term management of patients with mitochondrial encephalomyopathies, even though there are clinical limitations to the effects of this therapy.