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Sicheng Wang
Researcher at Second Military Medical University
Publications - 29
Citations - 474
Sicheng Wang is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 6, co-authored 9 publications receiving 169 citations.
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Journal ArticleDOI
Comparison between radial head replacement and open reduction and internal fixation in clinical treatment of unstable, multi-fragmented radial head fractures.
TL;DR: Compared with open reduction and internal fixation, radial head replacement with a metal prostheses resulted in favourable joint function for the unstable, multi-fragmented fractures of the radial head.
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Neutrophil-erythrocyte hybrid membrane-coated hollow copper sulfide nanoparticles for targeted and photothermal/ anti-inflammatory therapy of osteoarthritis
Xu Xue,Han Liu,Sicheng Wang,Yannan Hu,Biaotong Huang,Mengmeng Li,Jie Gao,Xiuhui Wang,Jiacan Su +8 more
TL;DR: In this article , a hybrid membranes-coated hollow copper sulfide nanoparticles (D-CuS@NR NPs) were fabricated for osteoarthritis (OA) treatment, which achieved the synergistic treatment of mild heating, prolonged circulation, and targeted delivery in this system.
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RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
Yan Hu,Xiaoqun Li,Zhi Xin,Wei Cong,Biaotong Huang,Huiwen Chen,Yajun Wang,Yinghua Li,Lipeng Wang,Chao Fang,Jiawei Guo,Ying Liu,Jin Cui,Cao Liehu,Weizong Weng,Qirong Zhou,Sicheng Wang,Chen Xiao,Su Jiacan +18 more
TL;DR: In this paper, a conditional deletion of the receptor activator of NF-κB ligand (RANKL) from BM adipose lineage cells was shown to increase the cancellous bone mass of long bones in mice by reducing the formation of trabecular osteoclasts and inhibiting bone resorption.
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Rational Design of Multifunctional CuS Nanoparticle‐PEG Composite Soft Hydrogel‐Coated 3D Hard Polycaprolactone Scaffolds for Efficient Bone Regeneration
Xu Xue,Hao Zhang,Han Liu,Sicheng Wang,Jiadong Li,Qirong Zhou,Xiao Chen,Xiaoxiang Ren,Yingying Jing,Yonghui Deng,Zhenhua Geng,Xiuhui Wang,Jiacan Su +12 more
TL;DR: It is demonstrated that the Dexp‐loaded CuS‐PEG‐hydrogel can effectively modify the 3D printed PCL scaffold, which has the potential to become an advanced drug delivery vehicle in the treatment of large bone defects.
Journal ArticleDOI
Triptolide prevents bone loss via suppressing osteoclastogenesis through inhibiting PI3K-AKT-NFATc1 pathway.
Jin Cui,Xiaoqun Li,Sicheng Wang,Yiming Su,Xiao Chen,Liehu Cao,Xin Zhi,Zili Qiu,Yao Wang,Hao Jiang,Biaotong Huang,Fang Ji,Jiacan Su +12 more
TL;DR: The new effect of anti‐cancer drug triptolide was demonstrated to be anti‐osteoclastogenesis, and triptoide might be a promising therapy for bone loss caused by tumour.