S
Silke Rath
Publications - 7
Citations - 505
Silke Rath is an academic researcher. The author has contributed to research in topics: Gut flora & Trimethylamine N-oxide. The author has an hindex of 4, co-authored 6 publications receiving 276 citations.
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Uncovering the trimethylamine-producing bacteria of the human gut microbiota
TL;DR: A diagnostic framework was developed that enabled the quantification and comprehensive characterization of the TMA-producing potential in human fecal samples and provides crucial information for the development of specific treatment strategies to restrain TMA producers and limit their proliferation.
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Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut.
TL;DR: This study gives a comprehensive overview of the diversity of bai-exhibiting bacteria in the human gut highlighting the application of metagenomics to unravel potential functions hidden from current isolates.
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Potential TMA-Producing Bacteria Are Ubiquitously Found in Mammalia.
TL;DR: Composition of TMA-forming communities was strongly influenced by diet and host taxonomy and despite their high correlation, both factors contributed uniquely to community structure.
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Pathogenic functions of host microbiota
TL;DR: This study outlines how this function-centric approach, where all members of a community exhibiting a particular pathofunction are redundant, can contribute to risk assessment and the development of precision treatment directing gut microbiota to increase host health.
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Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria.
Silke Rath,Katharina Rox,Sven Kleine Bardenhorst,Ulf Schminke,Marcus Dörr,Julia Mayerle,Fabian Frost,Markus M. Lerch,André Karch,Mark Brönstrup,Dietmar H. Pieper,Marius Vital +11 more
TL;DR: In this paper, a structural equation model was proposed to disentangle the different routes that promote higher TMAO levels with increasing age, demonstrating, for the first time, a functional role of gut microbiota in the process.