S
Silke Schelenz
Researcher at King's College
Publications - 78
Citations - 3624
Silke Schelenz is an academic researcher from King's College. The author has contributed to research in topics: Candida auris & Population. The author has an hindex of 28, co-authored 72 publications receiving 2913 citations. Previous affiliations of Silke Schelenz include University of London & University of East Anglia.
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Journal ArticleDOI
First hospital outbreak of the globally emerging Candida auris in a European hospital
Silke Schelenz,Ferry Hagen,Johanna Rhodes,Alireza Abdolrasouli,Anuradha Chowdhary,Anne Hall,Lisa Ryan,Joanne Shackleton,Richard Trimlett,Jacques F. Meis,Darius Armstrong-James,Matthew C. Fisher +11 more
TL;DR: This ongoing outbreak with genotypically closely related C. auris highlights the importance of appropriate species identification and rapid detection of cases in order to contain hospital acquired transmission.
Journal ArticleDOI
Candida auris: a Review of the Literature.
Anna Jeffery-Smith,Surabhi K. Taori,Silke Schelenz,Katie Jeffery,Elizabeth M. Johnson,Andrew M. Borman,Rohini Manuel,Colin S Brown,Colin S Brown +8 more
TL;DR: Genetic analysis indicates the simultaneous emergence of separate clades of this organism in different geographical locations, which will provide direction for further work in this field of Candida auris.
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Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris
Johanna Rhodes,Alireza Abdolrasouli,Rhys A. Farrer,Christina A. Cuomo,David M. Aanensen,Darius Armstrong-James,Matthew C. Fisher,Silke Schelenz +7 more
TL;DR: Multiple differential episodic selection of antifungal resistant genotypes has occurred within a genetically heterogenous population across this outbreak, creating a resilient pathogen and making it difficult to define local-scale patterns of transmission and implement outbreak control measures.
Journal ArticleDOI
A systematic review of the clinical, public health and cost-effectiveness of rapid diagnostic tests for the detection and identification of bacterial intestinal pathogens in faeces and food.
Ibrahim Abubakar,Lisa Irvine,Clare F Aldus,G. M. Wyatt,Richard Fordham,Silke Schelenz,Lee Shepstone,Amanda Howe,Michael W. Peck,Paul R. Hunter +9 more
TL;DR: The reviewed evidence shows that PCR for Campylobacter, Salmonella and E. coli O157 is potentially very successful in identifying pathogens, possibly detecting more than the number currently reported using culture; total replacement with rapid technologies may be feasible.
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Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: human surfactant protein D acts as an agglutinin for acapsular yeast cells.
TL;DR: Data indicate that collectins recognize carbohydrate structures in the cell wall of an initial infectious form of C. neoformans and may play a role in early antifungal defenses in the lung.