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Siyuan Hou
Researcher at Nanjing University
Publications - 7
Citations - 196
Siyuan Hou is an academic researcher from Nanjing University. The author has contributed to research in topics: Gene & Chemistry. The author has an hindex of 6, co-authored 6 publications receiving 144 citations.
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Journal ArticleDOI
Loss of conserved Gsdma3 self-regulation causes autophagy and cell death.
Peiliang Shi,An Tang,Li Xian,Siyuan Hou,Dayuan Zou,Ya-Su Lv,Zan Huang,Qinghua Wang,Anying Song,Zhaoyu Lin,Xiang Gao +10 more
TL;DR: Interestingly, it was found that the newly-generated null mutant of GSDma3 mice did not display the skin dysmorphology, indicating that Gsdma3 is not essential for differentiation of epidermal cells and maintenance of the hair cycle in normal physiological conditions.
Journal ArticleDOI
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a
TL;DR: It is found that lncRNA HOXD-AS1 was specifically upregulated in NSCLC tissues and promoted cancer cell growth by targeting miR-147a and the dual-luciferase reporter assay showed that HOxD-as1 could negatively regulate the expression of miR -147a.
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The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice.
TL;DR: It is found that Magea genes prevented stress-induced spermatogenic apoptosis after N-ethyl-N-nitrosourea (ENU) treatment during the adult stage and are crucial in maintaining normal testicular size and protecting germ cells from excessive apoptosis under genotoxic stress.
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Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity
Li Xian,Siyuan Hou,Zan Huang,An Tang,Peiliang Shi,Qinghua Wang,Anying Song,Shujun Jiang,Zhaoyu Lin,Shiying Guo,Xiang Gao +10 more
TL;DR: It is suggested that inhibition of hepatic Ppp2cα may be a useful strategy for the treatment of insulin resistance syndrome by improving glucose homeostasis and increased insulin sensitivity by activation of insulin signaling through Akt.
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Inhibition of PPARγ, adipogenesis and insulin sensitivity by MAGED1
Qinghua Wang,Qinghua Wang,Jing Tang,Shujun Jiang,Shujun Jiang,Zan Huang,Zan Huang,Anying Song,Siyuan Hou,Xiang Gao,Hai Bin Ruan +10 more
TL;DR: It is shown that MAGED1 expression was downregulated during adipogenesis and loss ofMAGED1 promoted preadipocyte proliferation and differentiation in vitro, and MAGED 1 might therefore serve as a novel pharmaceutical target to treat obesity-associated insulin resistance.