S
Snezana Agatonovic-Kustrin
Researcher at I.M. Sechenov First Moscow State Medical University
Publications - 125
Citations - 3642
Snezana Agatonovic-Kustrin is an academic researcher from I.M. Sechenov First Moscow State Medical University. The author has contributed to research in topics: Molecular descriptor & DPPH. The author has an hindex of 28, co-authored 118 publications receiving 2857 citations. Previous affiliations of Snezana Agatonovic-Kustrin include Universiti Teknologi MARA & Monash University Malaysia Campus.
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Artificial Neural Networks to Optimize Formulation Components of a Fixed- Dose Combination of Rifampicin, Isoniazid and Pyrazinamide in a Microemulsion
TL;DR: The results of this study indicate that the Artificial Neural Network can be successfully used to optimize the choice of solvents, solubilizing agents and surfactants prior to formulation of the microemulsion, limiting the amount of experiments, thus reducing the costs during the preformulation study.
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Development and validation of a simple high performance thin layer chromatography method combined with direct 1,1-diphenyl-2-picrylhydrazyl assay to quantify free radical scavenging activity in wine.
TL;DR: The total antioxidant capacity of the wine samples was mostly affected by the presence of resveratrol and rutin, while total polyphenolic content was mostly influenced by the absence of the less potent free radical scavengers gallic and caffeic acids.
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Quantification of Phenylpropanoids in Commercial Echinacea Products Using TLC with Video Densitometry as Detection Technique and ANN for Data Modelling
TL;DR: A novel method for quality control of herbal products, based on TLC separation, high-resolution digital plate imaging and ANN data analysis has been developed and can be adopted for routine evaluation of the phytochemical variability in Echinacea formulations available in the market.
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Molecular structural characteristics of estrogen receptor modulators as determinants of estrogen receptor selectivity.
TL;DR: The structural determinants and requirements necessary for estrogen receptors alpha and beta selectivity and ligand-receptor binding affinity and strategies likely to result in the development of a pharmacophore model that account for the differences in estrogenic effects between different ligands will be discussed.
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Quantification of polyphenolic antioxidants and free radical scavengers in marine algae
TL;DR: Although reversed phase plates are recommended for assessment of free radical scavengers, as they do not influence the free radical-antioxidant reaction, they may not provide the best separation of polar phenolic compounds, especially flavonoids, and therefore may not accurately quantify polyphenolic content and freeradical scavenging potential.