Artificial minichromosomes are exciting transgenic tools because they replicate and segregate autonomously and are not integrated into the host genome. They enable efficient delivery of an extremely large gene or multiple genes with high stability. There are two approaches to construct artificial minichromosomes: bottom-up and top-down. The construction of artificial minichromosomes addresses the basic questions of the structure and function of chromosomes. Advances in DNA synthesis technology will open a new era of generating artificial minichromosomes.

Which Is a Reliable Approach in the Generation of Artificial Minichromosomes, Bottom-Up or Top-Down?

Chromosome Information Service (CIS), XXIX

Chromosome Information Service (CIS), XVIII

1 Genetics and Environmental Toxicology Research Group, Department of Biology, Faculty of Science, Khon Kaen University, Muang, Khon Kaen 40002, Thailand 2 Biology Program, Faculty of Science and Technology, Prince of Songkla University, Muang, Pattani 94000, Thailand 3 Program in Computer Science, Faculty of Science, Buriram Rajabhat University, Muang, Buriram 31000, Thailand 4 Program in Applied Biology, Faculty of Science, Buriram Rajabhat University, Muang, Buriram 31000, Thailand 5 Biology Program, Faculty of Science, Ubonratchathani Rajabhat University, Ubon Ratchathani, Muang 34000, Thailand

The First Chromosome Analysis and Localization of the Nucleolar Organizer Region of Phayre's Flying Squirrel, Hylopetes phayrei (Rodentia, Sciuridae) in Thailand

Somsak Jeewattana

Papers

The First Chromosome Analysis and Localization of the Nucleolar Organizer Region of Phayre's Flying Squirrel, Hylopetes phayrei (Rodentia, Sciuridae) in Thailand