Showing papers by "Stacie M. Jones published in 1999"

Epinephrine Absorption in Children With a History of Anaphylaxis

Abstract: 1. Simons FER, 2. Roberts JR, 3. Gu A, 4. Simons KJ (1998) J Allergy Clin Immunol. 101:33–37. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] #### Purpose of the Study To study the clinical pharmacology of epinephrine in allergic children with a history of anaphylaxis. ##### Study Population A total of 17 children, ages 4 to 12 years old, with a history of severe allergies and systemic anaphylaxis. ##### Methods This was a randomized, single-blind, single-dose, parallel-group study. Subjects received either a subcutaneous injection of 0.01 mL/kg (maximum 0.3 ml [0.3 mg]) epinephrine solution or an intramuscular injection of 0.3 mL (0.3 mg) of epinephrine via an EpiPen Auto-Injector (Dey; … [1]: {openurl}?query=rft.jtitle%253DJournal%2Bof%2BAllergy%2Band%2BClinical%2BImmunology%26rft.stitle%253DJournal%2Bof%2BAllergy%2Band%2BClinical%2BImmunology%26rft.aulast%253DSimons%26rft.auinit1%253DF.%2BE.%26rft.volume%253D101%26rft.issue%253D1%2BPt%2B1%26rft.spage%253D33%26rft.epage%253D37%26rft.atitle%253DEpinephrine%2Babsorption%2Bin%2Bchildren%2Bwith%2Ba%2Bhistory%2Bof%2Banaphylaxis.%26rft_id%253Dinfo%253Adoi%252F10.1016%252FS0091-6749%252898%252970190-3%26rft_id%253Dinfo%253Apmid%252F9449498%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1016/S0091-6749(98)70190-3&link_type=DOI [3]: /lookup/external-ref?access_num=9449498&link_type=MED&atom=%2Fpediatrics%2F104%2FSupplement_2%2F366.2.atom [4]: /lookup/external-ref?access_num=000071539800006&link_type=ISI

Difficult-To-Control Asthma: Clinical Characteristics ofSteroid-Insensitive Asthma

Abstract: 1. Chan MTS, 2. Leung DYM, 3. Szefler SJ, 4. Spahn JD (1998) J Allergy Clin Immunol. 101:594–601. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] #### Purpose of the Study To better define patterns of response to oral glucocorticoids (GC) in adolescent asthmatics, to evaluate their clinical characteristics, and to determine the prevalence of steroid-insensitive asthma in this population. ##### Study Population A total of 164 adolescent patients, admitted to National Jewish Medical and Research Center between July 1993 and February 1997 for difficult-to-control asthma. ##### Methods This was a retrospective study of adolescents with asthma. Data collected included medical history, pulmonary function testing (PFT), methacholine challenge results, am cortisol levels, serum immunoglobulin E (IgE), total eosinophil counts (TEC), serum eosinophilic cationic protein (ECP), and soluble IL-2 receptor (IL-2R). Patients were first divided into two groups: those who required an oral GC burst … [1]: {openurl}?query=rft.jtitle%253DJournal%2Bof%2BAllergy%2Band%2BClinical%2BImmunology%26rft.stitle%253DJournal%2Bof%2BAllergy%2Band%2BClinical%2BImmunology%26rft.aulast%253DChan%26rft.auinit1%253DM.%2BT.%26rft.volume%253D101%26rft.issue%253D5%26rft.spage%253D594%26rft.epage%253D601%26rft.atitle%253DDifficult-to-control%2Basthma%253A%2Bclinical%2Bcharacteristics%2Bof%2Bsteroid-insensitive%2Basthma.%26rft_id%253Dinfo%253Adoi%252F10.1016%252FS0091-6749%252898%252970165-4%26rft_id%253Dinfo%253Apmid%252F9600494%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1016/S0091-6749(98)70165-4&link_type=DOI [3]: /lookup/external-ref?access_num=9600494&link_type=MED&atom=%2Fpediatrics%2F104%2FSupplement_2%2F388.1.atom [4]: /lookup/external-ref?access_num=000073697400005&link_type=ISI