S
Stefan Winkler
Researcher at University of Vienna
Publications - 48
Citations - 1498
Stefan Winkler is an academic researcher from University of Vienna. The author has contributed to research in topics: Plasmodium falciparum & CD8. The author has an hindex of 20, co-authored 48 publications receiving 1416 citations. Previous affiliations of Stefan Winkler include Albert Schweitzer Hospital.
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Journal ArticleDOI
High plasma levels of nitrogen oxides are associated with severe disease and correlate with rapid parasitological and clinical cure in Plasmodium falciparum malaria
Peter G. Kremsner,Stefan Winkler,Eckart Wildling,Javier Prada,Ulrich Bienzle,Wolfgang Graninger,Andreas K. Nussler +6 more
TL;DR: Plasma levels of nitrogen oxide, neopterin and CRP were compared in 3 groups of Gabonese patients with Plasmodium falciparum malaria before and after therapy to provide further evidence for the protective role of NO in malaria.
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Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production.
Peter G. Kremsner,Stefan Winkler,Christian Brandts,Eckart Wildling,L Jenne,Wolfgang Graninger,Javier Prada,Ulrich Bienzle,Pierre Juillard,Georges E. Grau +9 more
TL;DR: A high TNF production capacity during the acute phase of malaria predicted a rapid clinical and parasitologic cure in the patients, illustrating the dual role of TNF in the protection and pathology of malaria.
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Cytokine Profile and Correlation to the APACHE III and MPM II Scores in Patients with Sepsis
Elisabeth Presterl,Thomas Staudinger,Maria Pettermann,Andrea Lassnigg,Heinz Burgmann,Stefan Winkler,Michael Frass,Wolfgang Graninger +7 more
TL;DR: A significant decrease of the APACHE III scores, IL-6, and CRP levels was observed over the study period in the survivor group only, while neither the dynamics of TNF-alpha nor IL-12 plasma levels contributed to the risk estimation of mortality.
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Reciprocal Regulation of Th1- and Th2-Cytokine-Producing T Cells during Clearance of Parasitemia in Plasmodium falciparum Malaria
Stefan Winkler,Martin Willheim,Karin Baier,Daniela Schmid,Alexander Aichelburg,Wolfgang Graninger,Peter G. Kremsner,Peter G. Kremsner +7 more
TL;DR: A more pronounced Th2-driven immune response during acute untreated P. falciparum infection with a shift towards Th1 responsiveness induced by parasite clearance is suggested.
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Increased Serum Concentration of Soluble CD14 Is a Prognostic Marker in Gram-Positive Sepsis
Heinz Burgmann,Stefan Winkler,Gottfried J. Locker,Elisabeth Presterl,Klaus Laczika,Thomas Staudinger,Sylvia Knapp,Florian Thalhammer,Christoph Wenisch,Konstantin Zedwitz-Liebenstein,Michael Frass,Wolfgang Graninger +11 more
TL;DR: The serum level of sCD14 could be proven to be a good prognostic marker in the course of Gram-positive sepsis and increased levels are associated with a high mortality.