Showing papers by "Steffen Goletz published in 2014"
Patent•
22 Apr 2014
TL;DR: In this article, the use of anti-EGFR antibodies having improved glycosylation characteristics, in particular a reduced fucosylation, is provided which show anti-cancer efficacy and an improved adverse side effect profile.
Abstract: The present invention pertains to the field of cancer therapy using anti-cancer antibodies. The medical use of anti-EGFR antibodies having improved glycosylation characteristics, in particular a reduced fucosylation, is provided which show anti-cancer efficacy and an improved adverse side effect profile.
6 citations
Patent•
17 Jan 2014
TL;DR: In this article, the extracellular region of a glycophorin protein is derived from a protein to enhance the expression rate of proteins or peptides of interest when expressed as fusion protein together with said novel peptides.
Abstract: The present invention pertains to the field of recombinant protein production. Novel peptides derived from the extracellular region of a glycophorin protein are provided which enhance the expression rate of proteins or peptides of interest when expressed as fusion protein together with said novel peptides.
2 citations
Patent•
11 Dec 2014
TL;DR: In this article, the use of glycosylated peptides of the glycophorin protein and their use in medicine is discussed. But the peptides carry a carbohydrate structure of interest and are capable of binding to and being presented by MHC proteins.
Abstract: The present invention pertains to glycosylated peptides of the glycophorin protein and their use in medicine. In particular, the peptides carry a carbohydrate structure of interest and are capable of binding to and being presented by MHC proteins. Using the glycosylated glycophorin peptides, a specific immune response against the carbohydrate structure of interest can be induced.
1 citations
Patent•
17 Jan 2014
TL;DR: In this article, the extracellular region of a glycophorin protein is derived from a protein to enhance the expression rate of proteins or peptides of interest when expressed as fusion protein together with said novel peptides.
Abstract: The present invention pertains to the field of recombinant protein production. Novel peptides derived from the extracellular region of a glycophorin protein are provided which enhance the expression rate of proteins or peptides of interest when expressed as fusion protein together with said novel peptides.
1 citations