S
Steven E. Keller
Researcher at Rutgers University
Publications - 101
Citations - 4767
Steven E. Keller is an academic researcher from Rutgers University. The author has contributed to research in topics: Immune system & Population. The author has an hindex of 31, co-authored 92 publications receiving 4492 citations. Previous affiliations of Steven E. Keller include University of Medicine and Dentistry of New Jersey & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Suppression of Lymphocyte Stimulation Following Bereavement
TL;DR: In a prospective study of 15 spouses of women with advanced breast carcinoma, lymphocyte stimulation responses to phytohemagglutinin, concanavalin A, and pokeweed mitogen were significantly suppressed during the first two months following the death of a spouse compared with prebereavement levels.
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Stress-induced suppression of immunity in adrenalectomized rats.
TL;DR: The results demonstrate that corticosteroid independent mechanisms participate in the suppression of lymphocyte function by stressors, indicating that the modulation of immunity by stress is complex and multidetermined.
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Lymphocyte Function in Major Depressive Disorder
Steven J. Schleifer,Steven E. Keller,Arthur T. Meyerson,Marjorie Raskin,Kenneth L. Davis,Marvin Stein +5 more
TL;DR: Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls, which may be related to the altered neuroendocrine function found in patients with depressive disorders.
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Suppression of immunity by stress: Effect of a graded series of stressors on lymphocyte stimulation in the rat.
TL;DR: In rats a graded series of stressors produced progressively greater suppression of lymphocyte function, as measured by the number of circulating lymphocytes and by phytohemagglutinin stimulation, which suggests that stress suppresses immunity in proportion to the intensity of the stressor.
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Major Depressive Disorder and Immunity: Role of Age, Sex, Severity, and Hospitalization
TL;DR: No mean differences were found between the patients and matched controls in mitogen-induced lymphocyte proliferation, lymphocyte subsets, and natural killer cell activity, but depressed patients did not show increased lymphocyte responses or numbers of T4 lymphocytes with advancing age.