The Brain’s Heart – Therapeutic Opportunities for Patent Foramen Ovale (PFO) and Neurovascular Disease

International Headache Society published the International Classification of Headache Disorders 2nd Edition (ICHD‐II) in 2004. In response to this development, the “Clinical Practice Guideline for Chronic Headache” was compiled in Japan by the Study Group for Chronic Headache Clinical Practice Guideline Development. In 2006, the book entitled “The Clinical Practice Guideline for Chronic Headache (edited by Japanese Headache Society)” was published as the first edition. As triptans have become widely used, clinical practice for chronic headache has also been changed in Japan and there was a need to revise the first edition. Essentially based on the first edition, the new guideline has added the latest information and presented the concept of international standards of chronic headache care. This guideline included eight chapters and appendix: I. headache: general considerations, II. migraine, III. tension‐type headache, IV. trigeminal autonomic cephalalgias, V. other primary headache disorders, VI. medication‐overuse headache, VII. headaches in children, and VIII. genetics. We have published the second version in Japanese in 2013, but 1 month after we published the original guideline, the International Classification of Headache Disorders 3rd Edition beta version (ICHD‐3beta) was published. We changed this guideline to the new version in English based on ICHD‐3beta. This guideline is the final product of the Committee's efforts in 2015, which was opened in the home page of the Japanese Headache Society. This manuscript was written to show the main part of this guideline as Recommendation of each CQ. Among 121 CQs, only five CQ was selected to present full sentences including not only Recommendation but also other parts.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/ncn3.12322

Clinical practice guideline for chronic headache 2013

Perfusion abnormality on three-dimensional arterial spin labeling with a 3T MR system in pediatric and adolescent patients with migraine.

The aim of this research was to determine risk for family appearance of the
 recurrent headache (non-migraine and migraine). The recurrent headache can be
 understood as being a heterogeneous state, consisting of some more, still not
 found, hereditary disposition factors which altogether, interacting with
 surrounding factors give the recognizable clinical picture. The current
 heredity concept suggests multifactor heredity. The research was conducted in
 Vojvodina, the Northern Province of Serbia. The population of Vojvodina is
 around 2 million people belonging to more than 20 different ethnic groups.
 During the 20 years period (1988-2008), 30363 children aged 3 to 17 years
 were tested, independent of the place of birth. The presence of headaches
 similar to those tested was compared among all the members of the family
 within three generations. Positive family data of the recurrent headaches was
 detected among 98,6% children with migraine headaches, 64,7% children with
 non- migraine headaches, and 32,4% children without recurrent headaches. The
 relation among the members of the nuclear family (contingency quotient of
 0,429) is significantly stronger than the relation to the members of wider
 family (contingency quotient of 0,338). The probability of a child having the
 migraine headache, and not the non-migraine one, is 0,664 for a mother, 0,644
 for a father, 0,411 for a father`s mother, - 0,175 for a mother`s mother,
 0,165 for a mother`s father, and - 0,102 for a father`s father having similar
 recurrent headaches.

/pdf/recurrent-headache-and-migraine-within-the-family-3qo7a5jalp.pdf

Recurrent headache and migraine within the family

To assess the incidence of children with various types of migraine, an investigation was carried out from 1988 to 2008, on 30636 children (50.38% male, 49.62% female), in nine towns of the north province of Serbia. Migraine was reported in 8.63% children aged 3 to 17 (8.0% male, 9.6% female) as well as in 3.87% children aged 3-7 (4.2% boys, 3.57% girls). The proportion of children with either migraine or non-migraine headaches increased with their age, from 2.65% to 11.72% in boys, and from 2.71% to 15.86% in girls. Such increasing trend was also found for migraine with aura (from 1.8% to 32.7%). Children with migraine with aura showed their pick at the age of 9, while other migraine syndromes had the most frequent appearance at the age of 5 years. Migraine with aura accounted for 25.55%, migraine without aura for 67.21% and other migraine syndromes for 7.23% of investigated subjects with migraine. The average age of the migraine diagnosis was 5 years 1.8 months, while it was 4 years 11.4 months for migraine with aura, 5 years 7.2 months for migraine without aura and 3 years 7.2 months for other migraine syndromes. Migraine is much more frequent in second born children and in these from incomplete families. Migraine with aura appeared mostly in children coming from family with median socioeconomic welfare, while poor family welfare was predominant in children with migraine without aura. The length of breast-feeding influenced the appearance of the migraine in general, showing reciprocal influence of the length of breast-feeding on the appearance of migraine. Migraine was more often found (39.4%) among children who earlier joined nursery schools on a whole-day stay basis. Children with migraine have been diagnosed and treated by neuropaediatricians or neurologists in 55.4% cases (70.0% migraine with aura, 42.7% migraine without aura and 92.4% children with other migraine syndromes).

Stojadinovic

Papers

Migraine in children-migraine syndrome in children of Vojvodina.