Showing papers by "Sujita Kumar Kar published in 2018"

Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Abstract: Cognitive deficits are one of the core symptoms of schizophrenia that evolve during the course of schizophrenia, after being originated even before the onset of illness. Existing pharmacological and biological treatment modalities fall short to meet the needs to improve the cognitive symptoms; hence, various cognitive remediation strategies have been adopted to address these deficits. Research evidences suggest that cognitive remediation measures improve the functioning, limit disability bettering the quality of life. The functional outcomes of cognitive remediation in schizophrenia are resultant of neurobiological changes in specific brain areas. Recent years witnessed significant innovations in cognitive remediation strategies in schizophrenia. This comprehensive review highlights the biological correlates of cognitive deficits in schizophrenia and the remedial measures with evidence base.

Kluver–Bucy syndrome in an adolescent girl: A sequel of encephalitis

Abstract: 523 Journal of Pediatric Neurosciences ¦ Volume 13 ¦ Issue 4 ¦ October-December 2018 Dear Editor, Kluver–Bucy syndrome is a relatively rare phenomenon, which results from the involvement of bilateral temporal lobe, especially hippocampus and amygdala.[1] It is characterized by hyperorality, hypermetamorphosis (excessive exploration of the environment), altered sexual, feeding, and emotional behavior, and visual agnosia.[1] During childhood and adolescent, the manifestations differ. Many patients may have only few features of the syndrome and are described as “partial Kluver–Bucy syndrome.”[2] In pediatric population, it is infrequent and mostly results as a complication of herpes simplex encephalitis.[3] We present here the case of an adolescent female, who developed features of Kluver–Bucy syndrome following encephalitis.

Understanding the correlates of manic episode in a woman with insular glioma.

Abstract: Indian Journal of Psychiatry Volume 60, Issue 4, October-December 2018 511 4. Singh OP. District mental health program-need to look into strategies in the era of mental health care act, 2017 and moving beyond Bellary model. Indian J Psychiatry 2018;60:163-4. 5. Murthy RS. The national mental health programme: Progress and problem; mental health, an Indian perspective, 19462003. In: Agarwal SP, editor. Directorate General of Health Services. New Delhi: MOHFW; 2003. Access this article online

Acute and transient psychotic disorder as a rare early manifestation of late-onset sub-acute sclerosing panencephalitis

Abstract: Background Subacute Sclerosing Panencephalitis (SSPE) is a rare, late complication of measles infection. Illness generally starts with intellectual dysfunction, personality changes, myoclonus and epileptic seizures but rarely, initial presentations may only have psychiatric symptoms. Method The patient was hospitalized. Informed consent was obtained. History was reviewed. Detailed clinical examination was done. The patient was investigated in detail for his medical condition. Neurology consultation was done. Result We report a case of late-onset SSPE, presenting with symptoms of acute and transient psychotic disorder in the absence of classical symptoms of SSPE. Conclusion SSPE can have late onset presentation and psychosis can be its early manifestation.

Personality Changes in Bilateral Superior Frontal and Parafalcine Frontoparietal Polymicrogyria: A Rare Case Report.

Abstract: Polymicrogyria is a neurodevelopmental abnormality which results in the formation of excessive, small, abnormal, partially fused gyri with superficially located sulci replacing the normal gyral pattern. Intellectual disability, global developmental delay, epilepsy, language deficits, and motor deficits are commonly reported in patients with polymicrogyria. We present here the case of a young male with a rare pattern of bilateral superior frontal and parafalcine frontoparietal polymicrogyria, who had a mild intellectual disability, intractable seizures along with personality changes. This case report also highlights the relevance of neuroimaging in such cases, possible explanations of personality change in polymicrogyria and relevant management issues with a review of the literature.

The Lie Effect: A Factor Responsible for Perceived Therapeutic Response.

Abstract: Sir, Therapeutic effects of pharmacotherapy and somatic treatments are mediated through biological mechanisms. Other than the biological effects of medications, patients respond to pharmacotherapy or somatic treatments due to various other nonspecific reasons.[1] Recent evidence suggests that the therapeutic changes produced by the placebo too can be explained by definite psychobiological mechanisms.[2] Various other factors that contribute to therapeutic response may be spontaneous remission of the illness, underrating of the symptoms reported to the clinician, setting of the assessment, decrease in the stress level of the patient, good psychosocial support, and simultaneous use of other treatment measures.[3]