S
Surendra N. Pandeya
Researcher at Banaras Hindu University
Publications - 83
Citations - 3826
Surendra N. Pandeya is an academic researcher from Banaras Hindu University. The author has contributed to research in topics: Isatin & Semicarbazone. The author has an hindex of 26, co-authored 83 publications receiving 3560 citations. Previous affiliations of Surendra N. Pandeya include University of Saskatchewan.
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Synthesis, antibacterial, antifungal and anti-HIV activities of Schiff and Mannich bases derived from isatin derivatives and N-[4-(4′-chlorophenyl)thiazol-2-yl] thiosemicarbazide
TL;DR: Isatin, its 5-chloro and 5-bromo derivatives have been reacted with N-[4-(4'-chlorophenyl)thiazol-2-yl] thiosemicarbazide to form Schiff bases and the N-Mannich bases of these compounds were synthesized by reacting them with formaldehyde and three secondary amines.
Journal Article
Biological activities of isatin and its derivatives.
TL;DR: Isatin showed cardioinhibitory effect on frog heart, and hypotensive, respiratory depression and antidiuretic effects, and substituted indolinones showed antitubercular activity against M. tuberculosis H37Rv with MIC ranging from 10-20 microg mL(-1).
Journal Article
Anticonvulsant activity of Schiff bases of isatin derivatives.
TL;DR: N-methyl-5-bromo-3-(p-chlorophenylimino) isatin exhibited anticonvulsant activity in MES and ScMet with LD50 > 600 mg kg(-1), showing better activity than the standard drugs phenytoin, carbamazepine and valproic acid.
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Anticonvulsant activity of hydrazones, Schiff and Mannich bases of isatin derivatives.
TL;DR: The essential structural features responsible for interaction with receptor site are established within a suggested pharmacophore and all the active compounds showed greater protection than sodium valproate.
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Synthesis and antimicrobial activity of Schiff and Mannich bases of isatin and its derivatives with pyrimidine
TL;DR: Isatin and its derivatives have been reacted with 4-(4'-chlorophenyl)-6-(4"-methyl phenyl)-2-aminopyrimidine to form Schiff bases and the N-Mannich bases of these compounds were synthesized by reacting them with formaldehyde and several secondary amines.