S
Susan K. Hoiseth
Researcher at Stanford University
Publications - 1
Citations - 2090
Susan K. Hoiseth is an academic researcher from Stanford University. The author has contributed to research in topics: Auxotrophy & Aroa. The author has an hindex of 1, co-authored 1 publications receiving 2003 citations.
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Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines.
TL;DR: The use of a tetracycline-resistance transposon, Tn10 (refs 5, 6), inserted in gene aroA to produce non-reverting, aromatic-requiring derivatives of virulent S. typhimurium strains were virtually non-virulent; their use as live vaccines conferred excellent protection against challenge with a virulent strain.