Susan Repertinger

TL;DR: It is demonstrated that EGFR regulates multiple aspects of UV-induced inflammation and suggest activation of p38 kinase leading to increased COX-2 and cytokine expression as one mechanism through which it acts.

TL;DR: The data suggest that dysregulation of MYC gene may play a critical role in the pathogenesis of plasmablastic transformation, especially in cases with clonal evolution of low-grade lymphoproliferative disorders.

TL;DR: A 46-year-old man with episodic hypertension and headache is diagnosed with a pheochromocytoma of the left adrenal gland, and genetic mutation analyses for von-Hippel–Lindau, rearranged during transfection (RET), and succinate dehydrogenase complex subunit B (SDHB) genes were performed but failed to reveal any abnormalities within the tumor cells.

TL;DR: It is not uncommon for many physicians to remove a typical seborrheic keratosis without a confirmatory microscopic confirmation, so it is urged that all such lesions be examined by the pathologist to avoid missing another concomitant malignant lesion such as melanoma which needs adequate resection and close follow-up.

TL;DR: Immunohistochemical staining confirmed that the giant cells were of epithelial origin and that the proliferative rate of these cells was low, and another case occurring as a pedunculated, gluteal lesion in an 82-year-old man is reported.