S
Susan Wray
Researcher at National Institutes of Health
Publications - 109
Citations - 6642
Susan Wray is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gonadotropin-releasing hormone & Nasal placode. The author has an hindex of 48, co-authored 109 publications receiving 6270 citations. Previous affiliations of Susan Wray include University Hospitals of Cleveland & University of Rochester.
Papers
More filters
Journal ArticleDOI
Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode
TL;DR: The hypothesis that all LHRH cells in the central nervous system arise from a discrete group of progenitor cells inThe olfactory placode and that a subpopulation of these cells migrate into forebrain areas where they subsequently establish an adult-like distribution is supported.
Journal ArticleDOI
Spatiotemporal cell expression of luteinizing hormone-releasing hormone in the prenatal mouse: evidence for an embryonic origin in the olfactory placode
TL;DR: The spatiotemporal cell expression of luteinizing hormone-releasing hormone (LHRH) was investigated in mice during prenatal development using light microscopic immunocytochemistry to illustrate that LHRH cells express their peptide phenotype early in ontogeny and before their distribution in the forebrain is detected.
Journal ArticleDOI
Migratory arrest of gonadotropin-releasing hormone neurons in transgenic mice.
Sally Radovick,Susan Wray,Eric A. Lee,Donald K. Nicols,Yuko Nakayama,Bruce D. Weintraub,Heiner Westphal,Gordon B. Cutler,Frederic E. Wondisford +8 more
TL;DR: In transgenic mice expression of the simian virus 40 T antigen, driven by the promoter of human GnRH gene, resulted in central hypogonadism due to an arrest in neuronal migration during development and tumor formation along the migratory pathway.
Journal ArticleDOI
Neural Crest and Ectodermal Cells Intermix in the Nasal Placode to Give Rise to GnRH-1 Neurons, Sensory Neurons, and Olfactory Ensheathing Cells
TL;DR: Genetic Cre-lox lineage tracing of the neural crest versus ectodermal contribution to the developing nasal placode was performed and it is proved that the NC give rise to the olfactory ensheathing cells and subpopulations of GnRH-1 neurons, Olfactory and vomeronasal cells.
Journal ArticleDOI
From Nose to Brain: Development of Gonadotrophin‐Releasing Hormone ‐1 Neurones
TL;DR: The migration of GnRH‐1 cells is the best characterised example of neurophilic/axophilic migration, with the cells using a subset of olfactory‐derived vomeronasal axons as their pathway and numerous molecules to guide their movement into the forebrain.