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Suzanne Oparil

Researcher at Veterans Health Administration

Publications -  21
Citations -  1130

Suzanne Oparil is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Blood pressure & Coronary artery disease. The author has an hindex of 9, co-authored 21 publications receiving 1105 citations. Previous affiliations of Suzanne Oparil include Brigham and Women's Hospital.

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Volume-overload cardiac hypertrophy is unaffected by ACE inhibitor treatment in dogs

TL;DR: Upregulation of the AT1 receptor in the R-MR hearts may provide a mechanism by which normal intracardiac ANG II levels could continue to mediate LV hypertrophy, however, the mechanism of dissolution collagen weave in both N-MR and R- MR hearts may be related to the stretch of volume overload.
Journal ArticleDOI

Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation.

TL;DR: A positive correlation between LV diastolic wall stress and increased ACE activity with increased ANG II stores is demonstrated, suggesting that mechanical wall stress activated intracardiac ACE.