S
Sydney D. Finkelstein
Researcher at University of Pittsburgh
Publications - 218
Citations - 10634
Sydney D. Finkelstein is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Loss of heterozygosity & Carcinoma. The author has an hindex of 53, co-authored 216 publications receiving 10218 citations. Previous affiliations of Sydney D. Finkelstein include Drexel University & Hahnemann University Hospital.
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Journal ArticleDOI
Gene Expression Alterations in Prostate Cancer Predicting Tumor Aggression and Preceding Development of Malignancy
Yan Ping Yu,Douglas Landsittel,Ling Jing,Joel B. Nelson,Baoguo Ren,Lijun Liu,Courtney McDonald,Ryan Thomas,Rajiv Dhir,Sydney D. Finkelstein,George K. Michalopoulos,Michael J. Becich,Jianhua Luo +12 more
TL;DR: The results confirm an alteration of gene expression in prostate cancer when comparing with nontumor adjacent prostate tissues and indicate that the gene expression pattern in tissues adjacent to cancer is so substantially altered that it resembles a cancer field effect.
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Human polyoma virus-associated interstitial nephritis in the allograft kidney
Parmjeet Randhawa,Sydney D. Finkelstein,Velma P. Scantlebury,Ron Shapiro,Carlos Vivas,Mark L. Jordan,Maria M. Picken,Anthony J. Demetris +7 more
TL;DR: Polyoma virus tubulo-interstitial nephritis-associated graft dysfunction usually calls for judicious decrease in immunosuppression and monitoring for acute rejection, and development of methods to serially quantify the viral load in individual patients could potentially improve clinical outcome.
Journal Article
Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor α and β and show biological responses to estrogen
Laura P. Stabile,Autumn Gaither Davis,Christopher T. Gubish,Toni M. Hopkins,James D. Luketich,Neil A. Christie,Sydney D. Finkelstein,Jill M. Siegfried +7 more
TL;DR: It is suggested that estrogen signaling plays a biological role in both the epithelium and the mesenchyme in the lung and that estrogens could potentially promote lung cancer, either through direct actions on preneoplastic or neoplastic cells or through indirect actions on lung fibroblasts.
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Pancreatic cyst fluid DNA analysis in evaluating pancreatic cysts: a report of the PANDA study
Asif Khalid,Maliha Zahid,Sydney D. Finkelstein,Julia K. Leblanc,Neeraj Kaushik,Nuzhat A. Ahmad,William R. Brugge,Steven A. Edmundowicz,Robert H. Hawes,Kevin McGrath +9 more
TL;DR: Elevated amounts of pancreatic cyst fluid DNA, high-amplitude mutations, and specific mutation acquisition sequences are indicators of malignancy; the presence of a k-ras mutation is also indicative of a mucinous cyst.
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Expression of p53 and prognosis in children with malignant gliomas.
Ian F. Pollack,Sydney D. Finkelstein,Jeffrey Woods,Judith Burnham,Emiko J. Holmes,Ronald L. Hamilton,Allan J. Yates,James M. Boyett,Jonathan L. Finlay,Richard Sposto +9 more
TL;DR: Overexpression of p53 in malignant gliomas during childhood is strongly associated with an adverse outcome, independently of clinical prognostic factors and histologic findings.