T
T.Kuber Sampath
Publications - 1
Citations - 255
T.Kuber Sampath is an academic researcher. The author has contributed to research in topics: Osteocalcin & Alkaline phosphatase. The author has an hindex of 1, co-authored 1 publications receiving 252 citations.
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Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells.
TL;DR: It is shown that OP-1 acts on early stage mesenchymal progenitor cells (ATDC5, C3H10T1/2) to induce chondroblastic differentiation, while OP- 1 strongly enhances the osteoblastic phenotype of committed osteoblasts (MC3T3-E1), possibly explaining its induction of the endochondral ossification cascade in vivo.