T
T. Maiti
Researcher at Johns Hopkins University School of Medicine
Publications - 1
Citations - 818
T. Maiti is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Smoothened & Transmembrane protein. The author has an hindex of 1, co-authored 1 publications receiving 776 citations.
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Patched acts catalytically to suppress the activity of Smoothened
TL;DR: It is reported that Ptc and Smo are not significantly associated within Hh-responsive cells and it is suggested that the Ptc tumour suppressor functions normally as a transmembrane molecular transporter, which acts indirectly to inhibit Smo activity, possibly through changes in distribution or concentration of a small molecule.