T
T. Twaddell
Researcher at Autonomous University of Barcelona
Publications - 2
Citations - 1820
T. Twaddell is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Metastatic breast cancer & HER2/neu. The author has an hindex of 2, co-authored 2 publications receiving 1798 citations.
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Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.
José Baselga,Debasish Tripathy,John Mendelsohn,S. Baughman,Christopher C. Benz,L. Dantis,Nancy Sklarin,Andrew D. Seidman,Clifford A. Hudis,J. Moore,Paul Peter Rosen,T. Twaddell,I. C. Henderson,Larry Norton +13 more
TL;DR: RhuMAb HER2 is well tolerated and clinically active in patients with HER2-overexpressing metastatic breast cancers that had received extensive prior therapy and justifies further evaluation of this agent.
Journal Article
Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer.
José Baselga,D. Tripathy,John Mendelsohn,S. Baughman,C. C. Benz,L. Dantis,N. T. Sklarin,A. D. Seidman,C. A. Hudis,J. Moore,Paul Peter Rosen,T. Twaddell,I. C. Henderson,L. Norton +13 more
TL;DR: It is demonstrated that trastuzumab is well tolerated and clinically active in patients with HER2-overexpressing metastatic breast cancers who have received extensive prior therapy and the regression of human cancer through the targeting of putative growth factor receptors such as HER2 warrants further evaluation.