T
T. V. Nikitina
Researcher at Research Medical Center
Publications - 33
Citations - 244
T. V. Nikitina is an academic researcher from Research Medical Center. The author has contributed to research in topics: Karyotype & Aneuploidy. The author has an hindex of 8, co-authored 24 publications receiving 189 citations. Previous affiliations of T. V. Nikitina include Russian Academy & Russian Academy of Sciences.
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Journal ArticleDOI
Features of chromosomal abnormalities in spontaneous abortion cell culture failures detected by interphase FISH analysis.
TL;DR: The tissue-specific compartmentalization of cell lines with autosomal monosomies provides evidence that the aneuploidy of different human chromosomes may arise during different stages of intrauterine development.
Journal Article
Sex ratio in early embryonal mortality in man
TL;DR: A higher viability of XY embryos during the early stages of ontogenesis in man appears to explain their underrepresentation in samples of spontaneously aborted embryos and appears to be the major factor responsible for the deviation of the sex ratio from the theoretically expected value.
Journal ArticleDOI
Allele-Specific Biased Expression of the CNTN6 Gene in iPS Cell-Derived Neurons from a Patient with Intellectual Disability and 3p26.3 Microduplication Involving the CNTN6 Gene.
M.M. Gridina,N. M. Matveeva,Veniamin S. Fishman,A.G. Menzorov,Helen A. Kizilova,Nikolay A. Beregovoy,Igor I. Kovrigin,Inna E. Pristyazhnyuk,Igor P. Oscorbin,Maxim L. Filipenko,A. A. Kashevarova,Nikolay A. Skryabin,T. V. Nikitina,E. A. Sazhenova,Nazarenko Lp,Nazarenko Lp,Igor N. Lebedev,Igor N. Lebedev,Oleg L. Serov +18 more
TL;DR: Analysis of allele-specific expression of the CNTN6 gene in these neuronal cells by droplet digital PCR demonstrated that the level of expression in the duplicated allele was significantly reduced compared to that of the wild-type allele.
Journal ArticleDOI
About the sex ratio in connection with early embryonic mortality in man
TL;DR: A higher viability of XY embryos during the early stages of ontogenesis in man appears to explain their underrepresentation in samples of spontaneously aborted embryos and appears to be the major factor responsible for the deviation of the sex ratio from the theoretically expected value.
Journal ArticleDOI
Karyotype evaluation of repeated abortions in primary and secondary recurrent pregnancy loss
T. V. Nikitina,E. A. Sazhenova,Daria I. Zhigalina,E. N. Tolmacheva,N N Sukhanova,Igor N. Lebedev +5 more
TL;DR: The frequency of abnormalities is higher in abortions from the secondary RPL versusPrimary RPL group, and this difference is due to the relative deficiency of miscarriages with abnormal karyotypes in older women with primary RPL.