In general, in one aspect, the invention features systems, including a photonic crystal fiber including a core extending along a waveguide axis and a dielectric confinement region surrounding the core, the dielectric confinement region being configured to guide radiation along the waveguide axis from an input end to an output end of the photonic crystal fiber. The systems also includes a handpiece attached to the photonic crystal fiber, wherein the handpiece allows an operator to control the orientation of the output end to direct the radiation to a target location of a patient.

Photonic crystal fibers and medical systems including photonic crystal fibers

Fiber- or rod-based optical source featuring a large-core, rare-earth-doped photonic-crystal device for generation of high-power pulsed radiation and method

An implantable medical system comprises a therapy delivery module comprising a light source that generates light and a controller that controls the output of the light source, an optical light guide configured to deliver the light from the light source to a target tissue, a lead with a sense electrode for sensing bioelectric signals, and a sensing module configured to determine a patient therapeutic state based on the sensed bioelectric signals substantially simultaneously with the delivery of light from the light source, wherein the controller is configured to adjust the delivery of light to the target tissue based on the sensed patient therapeutic state.

Optical stimulation therapy

An apparatus and that provide an optical-fiber amplifier having at least one erbium-doped fiber section and an optical pump coupled to the erbium-doped fiber section, wherein the apparatus is operable to amplify signal pulses to high energy in the erbium-doped fiber section, the pulses having a wavelength in the range of about 1565 nm to about 1630 nm. In some embodiments, the amplifying fiber is ytterbium free.

High-energy eye-safe pulsed fiber amplifiers and sources operating in erbium's L-band

In general, in one aspect, the invention features a waveguide that includes a core extending along a waveguide axis and a confinement region surrounding the core. The confinement region includes a spiral portion and a non-spiral portion, wherein the spiral portion and the non-spiral portion extend along the waveguide axis.

Photonic crystal waveguides and systems using such waveguides

In general, in a first aspect, the invention features photonic crystal fibers that include a core extending along a waveguide axis, a confinement region extending along the waveguide axis surrounding the core, and a cladding extending along the waveguide axis surrounding the confinement region, wherein the cladding has an asymmetric cross-section.

Photonic crystal fibers having a preferred bending plane and systems that use such fibers

A self-cleaning photocatalytic composite membrane based on g-C3N4@MXene nanosheets for the removal of dyes and antibiotics from wastewater

Redox-active organic materials, as a new generation of sustainable resources, are receiving increasing attention in zinc ion batteries (ZIBs) due to their resource abundance and structure tunable. However, organic molecules with high potential are rare, and the voltage of most reported organic cathode-based ZIBs is less than 1.2 V. Herein, we explored the redox process of p-type organics and figured out the relationship between energy change and voltage output during the process. Then, we proposed a dual-step strategy to effectively tune the energy change and eventually improve the output voltage of the organic electrode. Combining the regulation on electron cloud of organic molecules and manipulation of the solvation structure, the output voltage of an organosulfur compound based ZIB was greatly increased from 0.8 V to 1.7 V. Our results put forward a specific pathway to improve the working voltage and lay the foundation for the practical application of organic electrodes.

High-Voltage Organic Cathodes for Zinc Ion Batteries through Electron Cloud and Solvation Structure Regulation.

The CO2 laser is the most widely used laser in laryngology, offering very precise cutting, predictable depth of penetration, and minimal collateral damage due to the efficient absorption of CO2 laser by water. Surgical applications of CO2 laser in microlaryngoscopy include removal of benign lesions and early-stage laryngeal cancer. A Transoral Laser Microsurgery (TLM) approach is routinely employed for treatment of laryngeal cancer; however, the role of TLM in advanced malignant lesions remains controversial. The main limiting factor of TLM is the restrictive exposure of the endoscopes combined with the limited cutting ability offered by the existing micromanipulator, enabling cutting only along the straight line-of-sight axis. A flexible fiber delivery system offering a very high quality output beam can offer tangential cutting and can therefore significantly enhance the existing surgical capabilities. Moreover, a flexible fiber for CO2 laser delivery can be used for treatment of benign conditions through flexible endoscopy in an office setting using local anesthesia. OmniGuide Communications Inc. (OGCI) has fabricated a photonic bandgap fiber capable of flexibly guiding CO2 laser energy. Results of laryngeal in-vivo and in-vitro animal studies will be presented. We will discuss the system setup, fiber performance and clinical outcomes. In addition we will present the results of the first human treatment and highlight additional otolaryngology conditions, which will likely benefit from the new technology herein presented.

Tairan Wang

Papers

Photonic crystal fibers and medical systems including photonic crystal fibers

Photonic crystal fibers having a preferred bending plane and systems that use such fibers

A self-cleaning photocatalytic composite membrane based on g-C3N4@MXene nanosheets for the removal of dyes and antibiotics from wastewater

High-Voltage Organic Cathodes for Zinc Ion Batteries through Electron Cloud and Solvation Structure Regulation.

OmniGuide photonic bandgap fibers for flexible delivery of CO2 laser energy for laryngeal and airway surgery