J. Appl. Cryst.の発刊に際して

The recent advances in nanotechnology and the corresponding increase in the use of nanomaterials in products in every sector of society have resulted in uncertainties regarding environmental impacts. The objectives of this review are to introduce the key aspects pertaining to nanomaterials in the environment and to discuss what is known concerning their fate, behavior, disposition, and toxicity, with a particular focus on those that make up manufactured nanomaterials. This review critiques existing nanomaterial research in freshwater, marine, and soil environments. It illustrates the paucity of existing research and demonstrates the need for additional research. Environmental scientists are encouraged to base this research on existing studies on colloidal behavior and toxicology. The need for standard reference and testing materials as well as methodology for suspension preparation and testing is also discussed.

Nanomaterials in the environment: Behavior, fate, bioavailability, and effects

Chem. Pharm. Bull.(オピニオン)

http://hwhuang.rice.edu/pdfs/Yang2001.pdf

Barrel-Stave Model or Toroidal Model? A Case Study on Melittin Pores

This Account reviews our main achievements in the field of excited-state properties of fullerene derivatives. The photosensitizing and electron-acceptor features of some relevant classes of functionalized fullerene materials are highlighted, considering the impact of functionalization on fullerene characteristics. In addition, the unique optimization in terms of redox potentials, water-solubility, and singlet oxygen generation is presented for several novel fullerene-based materials.

Excited-state properties of C(60) fullerene derivatives.

The Synthesis of Novel Polycyclic Heterocyclic Ring Systems. Part 2. Naphtho(2,1-b:4,3-g)bisbenzo(b)thiophene.

In the title compound, C14H13ClN2O, the fused hydro­pyrimidine ring adopts an envelope conformation with one of the methyl­ene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44 (11)°. In the crystal, mol­ecules are linked by a weak C—H⋯π inter­action, forming a helical chain along the c axis.

https://journals.iucr.org/e/issues/2012/11/00/ff2085/ff2085.pdf

10'-Chloro-3',4'-dihydro-2'H-spiro-[cyclo-propane-1,7'(6'H)-pyrimido[2,1-a]isoquinolin]-6'-one.

Several compound libraries are prepared including compounds (III) and other compounds derived from (III), e.

Polycyclic N-Heterocyclic Compounds. Part 75. Synthesis of 2,4-Disubstituted 5,6-Dihydro[1]benzoxepino[5,4-d]pyrimidines and 12-Substituted 1,2,4,5-Tetrahydro[1]benzoxepino[4,5-e]imidazo[1,2-c]pyrimidines as Potential Antiplatelet Aggregators.

A series of title compounds is prepared and tested for their antiplatelet aggregation activity.

Polycyclic N-Heterocyclic Compounds. Part 77. Synthesis of [1]Benzothieno[3′,2′:2,3]oxepino[4,5-d]pyrimidines and Evaluation of Their Antiplatelet Aggregation Activity.

Takashi Hirota

Papers

The Synthesis of Novel Polycyclic Heterocyclic Ring Systems. Part 2. Naphtho(2,1-b:4,3-g)bisbenzo(b)thiophene.

10'-Chloro-3',4'-dihydro-2'H-spiro-[cyclo-propane-1,7'(6'H)-pyrimido[2,1-a]isoquinolin]-6'-one.

Polycyclic N-Heterocyclic Compounds. Part 75. Synthesis of 2,4-Disubstituted 5,6-Dihydro[1]benzoxepino[5,4-d]pyrimidines and 12-Substituted 1,2,4,5-Tetrahydro[1]benzoxepino[4,5-e]imidazo[1,2-c]pyrimidines as Potential Antiplatelet Aggregators.

Polycyclic N-Heterocyclic Compounds. Part 77. Synthesis of [1]Benzothieno[3′,2′:2,3]oxepino[4,5-d]pyrimidines and Evaluation of Their Antiplatelet Aggregation Activity.

Synthesis of 1,3,10-triazaphenanthrene part 1