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Showing papers by "Tammo Diercks published in 2009"

Journal Article•DOI•
Fluorinated carbohydrates as lectin ligands: versatile sensors in 19F-detected saturation transfer difference NMR spectroscopy

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Tammo Diercks, João P. Ribeiro1, F. Javier Cañada1, Sabine André2, Jesús Jiménez-Barbero1, Hans-Joachim Gabius2 •
Spanish National Research Council1, Ludwig Maximilian University of Munich2
02 Jun 2009-Chemistry: A European Journal
TL;DR: As a novel approach for studying carbohydrate-lectin interactions spectroscopically, the resolution and specificity of (19)F-detected NMR spectroscopy with the sensitivity of the saturation transfer difference (STD) technique are combined.
Abstract: As a novel approach for studying carbohydrate-lectin interactions spectroscopically, we combine the resolution and specificity of (19)F-detected NMR spectroscopy with the sensitivity of the saturation transfer difference (STD) technique. The resulting background-free (19)F-STD spectra open a promising perspective for broad application with medical relevance, for example, in drug discovery.

55 citations