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Thomas A. Down
Researcher at Wellcome Trust/Cancer Research UK Gurdon Institute
Publications - 46
Citations - 16476
Thomas A. Down is an academic researcher from Wellcome Trust/Cancer Research UK Gurdon Institute. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 34, co-authored 46 publications receiving 15651 citations. Previous affiliations of Thomas A. Down include Wellcome Trust Sanger Institute & Novartis Institute for Tropical Diseases.
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What can we learn from noncoding regions of similarity between genomes
Thomas A. Down,Tim Hubbard +1 more
TL;DR: The results presented here indicate that the promoter signal is the strongest single motif-based signal in the non-coding functional fraction of the genome, and lend support to the belief that there exists a substantial subset of promoter regions which share several common features including, but not restricted to, a relative abundance of CpG dinucleotides.