T
Thomas G. Gross
Researcher at National Institutes of Health
Publications - 293
Citations - 12243
Thomas G. Gross is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 55, co-authored 281 publications receiving 10635 citations. Previous affiliations of Thomas G. Gross include University of California, Los Angeles & University of Cincinnati.
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Journal ArticleDOI
Real-World Evidence — What Is It and What Can It Tell Us?
Rachel E. Sherman,Steven A. Anderson,Gerald J. Dal Pan,Gerry W. Gray,Thomas G. Gross,Nina L. Hunter,Lisa M. LaVange,Danica Marinac-Dabic,Peter W. Marks,Melissa A. Robb,Jeffrey Shuren,Robert Temple,Janet Woodcock,Lilly Q. Yue,Robert M. Califf +14 more
TL;DR: The FDA is developing guidance on the use of “real-world evidence” — health care information from atypical sources, including electronic health records, billing databases, and product and disease registries — to assess the safety and effectiveness of drugs and devices.
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Malignancy after transplantation.
TL;DR: Although calcineurin inhibitors and azathioprine have been linked with posttransplant malignancies, newer agents such as mycophenolate mofetil and sirolimus have not and indeed may have antitumor properties and long-term data are needed to determine if the use of these agents will ultimately lower the mortality due to malignancy for transplant recipients.
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X-linked lymphoproliferative disease: twenty-five years after the discovery.
Thomas A. Seemayer,Thomas G. Gross,R M Egeler,Samuel J. Pirruccello,Jack R. Davis,C M Kelly,Motohiko Okano,Arpad Lanyi,Janos Sumegi +8 more
TL;DR: The X-linked lymphoproliferative disease (XLP), one of six described X- linked immunodeficiencies, stems from a mutation at Xq25 which renders males impotent to mount an effective immune response to the ubiquitous EBV.
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Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge
Carlos Rodriguez-Galindo,Paola Friedrich,Patricia Alcasabas,Federico Antillon,Shripad Banavali,Luis Castillo,Trijn Israels,Sima Jeha,Mhammed Harif,Michael J. Sullivan,Thuan Chong Quah,Catherine Patte,Ching-Hon Pui,Ronald D. Barr,Thomas G. Gross +14 more
TL;DR: Childhood cancer burden has been shifted toward low- and middle-income countries and, for that reason, global initiatives directed at pediatric cancer care and control are needed.
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Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: a cautionary tale?
TL;DR: The issue of lymphoma and IBD therapy is reviewed and clinical options in light of this new information are explored.