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Thomas Gregor Issac

Researcher at National Institute of Mental Health and Neurosciences

Publications -  51
Citations -  311

Thomas Gregor Issac is an academic researcher from National Institute of Mental Health and Neurosciences. The author has contributed to research in topics: Dementia & Frontotemporal dementia. The author has an hindex of 8, co-authored 46 publications receiving 222 citations.

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Vitamin B12 Deficiency: An Important Reversible Co-Morbidity in Neuropsychiatric Manifestations

TL;DR: Cognitive decline in Vitamin B12 deficiency was significantly associated with increased serum cholesterol and was significantly prevalent in neurological disorders when compared with primary psychiatric illnesses and it increases the load of cognitive decline and accentuates vascular risk factors in neuropsychiatric illnesses.
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Apraxias in neurodegenerative dementias

TL;DR: Recognition of the apraxias help in establishing organicity, categorization, caregiver education, early strategies for treatment, avoiding anti-psychotics and introducing disease modifying pharmacotherapeutic agents and also prognosticating.
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Vitamin D status and vascular dementia due to cerebral small vessel disease in the elderly Asian Indian population.

TL;DR: Screening for vitamin D status in addition to regular monitoring of blood pressure, could reduce the risk of VaD associated with cerebral SVD in the elderly Asian Indian subjects.
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Transcranial magnetic stimulation in patients with early cortical dementia: A pilot study

TL;DR: The most consistent observation was that SP was reduced and there were escape discharges noticed during the SP suggesting increased cortical excitability and decreased cortical inhibition suggesting early asymptomatic changes in the gamma-aminobutyric acid and cholinergic system is taking place.
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Autonomic dysfunction: A comparative study of patients with Alzheimer's and frontotemporal dementia - A pilot study.

TL;DR: In this paper, a study revealed autonomic dysfunction in patients with frontotemporal dementia (FTD) and Alzheimer's disease (AD) using LabChart and SPSS.