Showing papers by "Thomas H. Jukes published in 1936"
TL;DR: It is proposed for the sake of brevity to refer to the factor present in the concentrate as the “filtrate factor,” in reference to the method of preparation by its discoverers, which intentionally leaves in abeyance the question of the identity or non-identity of the factor.
38 citations
34 citations
TL;DR: Birch, György and Harris 5 concluded that the human “P-P” factor and the canine anti-blacktongue factor are different, both from the rat vitamin B6 and from lactoflavin, and that the canineAnti- blacktongsue factor may be identical with the “ P-P" factor.
Abstract: Gyorgy,1 Elvehjem and Koehn,2 and Lepkovsky and Jukes3,4 have divided the vitamin B2 complex into 3 components—flavins, the rat antiacrodynia (vitamin B6) factor, and the filtrate or chick antidermatitis factor. Birch, Gyorgy and Harris5 concluded that the human “P-P” factor and the canine anti-blacktongue factor are different, both from the rat vitamin B6 and from lactoflavin, and that the canine anti-blacktongue factor may be identical with the “P-P” factor. They found that pellagra-and blacktongue-producing diets were rich in vitamin B6. Maize was especially rich. Dogs fed on a purified diet supplemented with vitamin B1 and lactoflavin could not be cured of blacktongue unless both maize (rat vitamin B6) and liver extract were added to the diet. Dann6 likewise found that both yellow and white maize contained goodly amounts of vitamin B6. Dann,6 and Spies and Chinn, as quoted by Birch, et al.,5 were unable to cure pellagrins with lactoflavin. The experimental evidence of Jukes and Lepkovsky7 indicates th...
11 citations