The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

Harrison's Principles of Internal Medicine

Secret History: Return of the Black Death Channel 4, 7-8pm In 1348 the Black Death swept through London, killing people within days of the appearance of their first symptoms. Exactly how many died, and why, has long been a mystery. This Secret History documentary follows experts as they pick through the evidence and reveal why the plague killed on such a scale. And they ask, what might be coming next?

Medscape

Pathology and genetics of tumors of soft tissue and bone

https://www.chpso.org/sites/main/files/file-attachments/chest-2008-geerts-381s-453s.pdf

Prevention of Venous Thromboembolism* American College of Chest Physicians Evidence- Based Clinical Practice Guidelines (8th Edition)

Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk S50

The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular diseases (CVD); improve the management of people who have these diseases through professional education and research; and develop guidelines, standards, and policies that promote optimal patient care and cardiovascular health. Toward these objectives, the ACC and AHA have collaborated with the National Heart, Lung, and Blood Institute (NHLBI) and stakeholder and professional organizations to develop …

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2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

As the Japanese population has aged rapidly, Japan's experience has implications for other high-income countries, including the United States. The aging of Japan's population, coupled with the government's decision to implement a public long-term care insurance program in 2000, has increased the nation's expenditures. In acute care, costs have been relatively contained by biennially revising the fee schedule for all physician and hospital services and by lowering pharmaceutical prices. The fee schedule not only sets prices but also controls volume by setting the conditions of billing for each item. This fee schedule is applied to all social health insurance plans (which enroll all permanent residents of Japan) and to virtually all providers. In contrast, despite the use of a similar fee schedule, spending in long-term care insurance has increased more than spending in health care. This is both because long-term care became an entitlement and because aging has had a greater impact on long-term care insurance spending than on health insurance spending. In this article we analyze Japanese expenditure data to provide essential information to the US as the percentage of its population ages sixty-five and older continues to rise. A key lesson that the US can learn from Japan's experience is that as its population ages, the need for long-term care will increase, necessitating better control of acute care spending.

Controlling Spending For Health Care And Long-Term Care: Japan's Experience With A Rapidly Aging Society.

Minimally invasive thoracic surgical techniques appear to reduce important morbidity and facilitate return to normal activity when compared with standard open approaches [1–3]. Mechanisms for this benefit likely include reduction in pain, earlier ambulation, and decreased inflammatory response to injury [3–6]. Before such techniques are routinely adopted, however, it is incumbent upon thoracic surgeons to demonstrate that therapeutic benefit of the procedure is not compromised. For resection of lung cancer, this means there must be comparable completeness of resection with appropriate lymph node sampling or lymphadenectomy [2, 7–9].

Minimally Invasive Approaches to Lung Cancer

Xu and colleagues propose the ambitious tasks of evaluating in gastric cancer patients “the long-term effect of number of examined lymph nodes on the prognosis of patients,” and exploring “the optimal number of lymph nodes for accurate staging in patients with node-negative gastric cancer after D2 dissection” (1). These two distinctly different goals require very dissimilar analytic strategies. To our surprise, they report one number, not two: 16. The question persists—“Is there a magic number of resected lymph nodes that ensures an optimal lymphadenectomy for gastric cancer?”

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Thomas W. Rice

Papers

Controlling Spending For Health Care And Long-Term Care: Japan's Experience With A Rapidly Aging Society.

Minimally Invasive Approaches to Lung Cancer

Optimal lymphadenectomy for gastric cancer: is there a magic number?