T
Thomas Wichmann
Researcher at Johns Hopkins University
Publications - 4
Citations - 3179
Thomas Wichmann is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Subthalamic nucleus & Basal ganglia. The author has an hindex of 3, co-authored 4 publications receiving 3081 citations.
Papers
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Journal ArticleDOI
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
TL;DR: The postulated role of excessive activity in the subthalamic nucleus in Parkinson's disease is supported by the effects of lesions evaluated in monkeys rendered parkinsonian by treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal ArticleDOI
The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
TL;DR: periodic oscillatory neuronal activity at low frequency, highly correlated with tremor, was detected in a large number of cells in STN and GPi after MPTP treatment and the autocorrelograms of spike trains of these neurons confirm that the periodic oscillatory activity was very stable.
Book ChapterDOI
Neurotransmitters and Disorders of the Basal Ganglia
Thomas Wichmann,Mahlon R. DeLong +1 more
TL;DR: The basal ganglia are implicated in a large number of behaviors, including self-initiated (internally generated) movements, procedural learning, scaling of movement parameters, and movement sequencing.