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Tianyu Zhou
Researcher at Peking University
Publications - 11
Citations - 102
Tianyu Zhou is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 7 publications receiving 60 citations. Previous affiliations of Tianyu Zhou include Shanghai Jiao Tong University.
Papers
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Journal ArticleDOI
Fine particulate matter (PM2.5) aggravates apoptosis of cigarette-inflamed bronchial epithelium in vivo and vitro
TL;DR: PM2.5 aggravated apoptosis in cigarette-inflamed bronchial epithelial cells and the responses could be suppressed by Z-VAD-FMK, a pan-caspase inhibitor, and the results gave a new idea about the mechanism of PM2.
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PM2.5 downregulates miR-194-3p and accelerates apoptosis in cigarette-inflamed bronchial epithelium by targeting death-associated protein kinase 1.
TL;DR: It is suggested that miR-194-3p was a protective regulator involved in apoptosis pathway and a potential therapeutic target for treatment of bronchial epithelial injury aggravation induced by PM2.5.
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A pilot study of blood microRNAs and lung function in young healthy adults with fine particulate matter exposure
TL;DR: This pilot study identified differentially expressed blood miRNAs contrasting COPD participants without diagnose of COPD or related treatment before and matched control and found only miR-194-3p showed a positive statistically correlation with lag0-1 forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) during exposure of PM2.5.
Journal ArticleDOI
Proteomics of exhaled breath condensate in stable COPD and non-COPD controls using tandem mass tags (TMTs) quantitative mass spectrometry: A pilot study
Chao Sun,Tianyu Zhou,Tianyu Zhou,Gaoqiang Xie,Shuqian Fu,Lingling Gao,Jiping Liao,Yangfeng Wu,G L Wang +8 more
TL;DR: Individual EBC samples are analyzed, which would deepen the understanding of the pathogenesis of COPD, and some proteins might be novel biomarkers of EBC in COPD and TMTs was available to analyze proteomics in individual E BC samples.
Journal ArticleDOI
A prospective study of salvational intervention with ICS/LABA for reducing chronic obstructive pulmonary disease exacerbation under severe air pollution (SIRCAP) in Beijing: protocol of a multi-center randomized controlled trial
Tianyu Zhou,Yijue Zhong,Jiping Liao,Guangfa Wang,Xueying Li,Xiao-sen Qian,Pingchao Xiang,Xinsheng Chen,Zhenyang Xu,Feng-zhen Zhang,Xiaoguang Wang,Senlin Wang,Xiangxin Li,Chunxiao Yu,Y. Zhang,Guoguang Xia,Li Dai +16 more
TL;DR: The salvational intervention is a novel strategy for COPD management under severe air pollution and will provide reference information to guide clinical practice in reducing the air pollution related exacerbation of COPD.