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Showing papers by "Tiia Ngandu published in 2010"

Journal Article•DOI•
Midlife smoking, apolipoprotein E and risk of dementia and Alzheimer's disease: a population-based cardiovascular risk factors, aging and dementia study

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Minna Rusanen1, Suvi Rovio2, Tiia Ngandu3, Aulikki Nissinen3, J. Tuomilehto, Hilkka Soininen1, Miia Kivipelto1 •
University of Eastern Finland1, Karolinska Institutet2, National Institutes of Health3
20 Sep 2010-Dementia and Geriatric Cognitive Disorders
TL;DR: Midlife smoking was associated with an increased risk of dementia and AD later in life only among those individuals carrying the APOE Ε4 allele, suggesting that the association between smoking and AD may be complex and vary according to genotype.
Abstract: Aim: To elucidate the effect of midlife smoking on the risk of dementia and Alzheimer’s disease (AD), and the possible modification of this relation by the apolipoprotein E (APOE) &

69 citations