T
Tilman Ahlfeld
Researcher at Dresden University of Technology
Publications - 39
Citations - 1341
Tilman Ahlfeld is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Medicine & 3D bioprinting. The author has an hindex of 16, co-authored 31 publications receiving 737 citations.
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Journal ArticleDOI
Development of a clay based bioink for 3D cell printing for skeletal application.
Tilman Ahlfeld,Gianluca Cidonio,David Kilian,Sarah Duin,Ashwini Rahul Akkineni,Jonathan I. Dawson,Shoufeng Yang,Anja Lode,Richard O.C. Oreffo,Michael Gelinsky +9 more
TL;DR: The authors used a synthetic nanosilicate clay, called Laponite, to build up scaffolds utilising the extrusion-based method 3D plotting, achieving scaffolds with high printing fidelity.
Journal ArticleDOI
Bioprinting of mineralized constructs utilizing multichannel plotting of a self-setting calcium phosphate cement and a cell-laden bioink.
Tilman Ahlfeld,Falko Doberenz,David Kilian,Corina Vater,P. Korn,Günter Lauer,Anja Lode,Michael Gelinsky +7 more
TL;DR: The manuscript discusses possible impacts of the CPC setting reaction on cells within the bioink and illustrates the advantages of CPC in bioprinting as alternative to the commonly used thermoplasts for bone tissue engineering.
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Design and Fabrication of Complex Scaffolds for Bone Defect Healing: Combined 3D Plotting of a Calcium Phosphate Cement and a Growth Factor-Loaded Hydrogel
Tilman Ahlfeld,Ashwini Rahul Akkineni,Yvonne Förster,Tino Köhler,Sven Knaack,Michael Gelinsky,Anja Lode +6 more
TL;DR: This study developed a strategy for growth factor loading based on multichannel plotting: a biphasic scaffold design was realised combining CPC with VEGF-laden, highly concentrated hydrogel strands, which can be applied for testing in a rat critical size femur defect.
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3D Bioprinting of osteochondral tissue substitutes - in vitro-chondrogenesis in multi-layered mineralized constructs
David Kilian,Tilman Ahlfeld,Ashwini Rahul Akkineni,Anne Bernhardt,Michael Gelinsky,Anja Lode +5 more
TL;DR: The presence of a mineralized zone as located in the physiological calcified cartilage region suspected to interfere with chondrogenesis, was found to support Chondrogenic ECM production by altering the ionic concentrations of calcium and phosphorus in in vitro culture conditions.
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A versatile method for combining different biopolymers in a core/shell fashion by 3D plotting to achieve mechanically robust constructs.
TL;DR: It is shown that core as well as shell part can be loaded with growth factors and that the release depends on core composition and shell thickness, and that this new strategy can be used for bioprinting purposes as well.