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Showing papers by "Tilman B. Drüeke published in 1977"

Journal Article•DOI•
Effects of high dialysate calcium concentration on bone remodelling, serum biochemistry, and parathyroid hormone in patients with renal osteodystrophy

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Tilman B. Drüeke1, Philippe Bordier1, N. K. Man1, Paul Jungers1, Pierre Marie1 •
Necker-Enfants Malades Hospital1
01 Apr 1977-Kidney International
TL;DR: It is concluded that providing additional calcium (using a dialysate calcium concentration of 8.0 mg/100 ml), the goal of which was to decrease secondary hyperparathyroidism, proved to be successful only in one patient and failed to do so in the five others.

13 citations

Book Chapter•DOI•
Effect of parathyroid hormone and volume expansion on jejunal calcium, sodium, and water transport in the rat.

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Tilman B. Drüeke1, Jacques Chanard1, Eric Pujade-Lauraine1, Bernard Lacour1, J. L. Funck-Brentano1 •
University of Paris1
01 Jan 1977-Advances in Experimental Medicine and Biology
TL;DR: It is suggested that PTH has a direct inhibitory effect on jejunal calcium, sodium, and water absorption.
Abstract: It seems well established that parathyroid hormone (PTH) increases intestinal calcium absorption and that this effect is indirect, possibly via enhanced production of 1,25 dihydroxy-cholecalciferol (1, 25-(OH)2 D3) by the kidney (1, 2). The time-lag between PTH administration and 1,25-(OH)2D3 synthesis is likely to be several hours (2). A possible direct PTH effect on the intestine in the absence of 1,25-(OH)2D3 mediation remains questionable.

1 citations