Tivadar Farkas

TL;DR: A series of experiments and measurements demonstrate the importance of minimizing the extra-column band broadening contribution of the instrument used and the combination of several measures allowed the achievement of the full potential efficiency of three Kinetex-C(18) columns, using a conventional liquid chromatograph.

TL;DR: Three polysaccharide-derived chiral stationary phases (CSPs) were evaluated for the resolution of more than 200 racemic compounds of pharmaceutical interest in the reversed-phase (RP) separation mode and cellulose tris(3-chloro-4-methylphenylcarbamate) and amylosetris(2- chloro-5- methylphenyl carbamate) emerge as CSPs of wide applicability in either commonly used separation modes rivaling such well

TL;DR: The mechanism of particle consolidation under stress explains the origin of this phenomenon and provides a fundamental justification to what is known in column chromatography as "the wall effect".

TL;DR: In this article, the radial distributions of the local linear velocity of the mobile phase, the local efficiency, and the local analyte concentration were determined at the outlet of 0.3−0.4 in. i.d.

TL;DR: In this article, the spatial distribution of analyte molecules within the chromatographic zone at the column exit was determined for a commercial column and for several laboratory-packed columns made with different solid particles and with a commercial silica-based stationary phase.