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Tobias Franiel

Researcher at Charité

Publications -  66
Citations -  2039

Tobias Franiel is an academic researcher from Charité. The author has contributed to research in topics: Prostate cancer & Prostate. The author has an hindex of 20, co-authored 59 publications receiving 1841 citations. Previous affiliations of Tobias Franiel include University of Jena & Memorial Sloan Kettering Cancer Center.

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Diffusion-weighted Endorectal MR Imaging at 3 T for Prostate Cancer: Tumor Detection and Assessment of Aggressiveness

TL;DR: Combined DW and T2-weighted MR imaging had similar performance to T1-weighting MR imaging alone for tumor detection; however, DW MR imaging provided additional quantitative information that significantly correlated with prostate cancer aggressiveness.
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Areas suspicious for prostate cancer: MR-guided biopsy in patients with at least one transrectal US-guided biopsy with a negative finding--multiparametric MR imaging for detection and biopsy planning.

TL;DR: Only the combination of T2-weighted imaging with all three multiparametric techniques depicts all identifiable prostate cancers; a double combination with DW imaging and (1)H MR spectroscopy or contrast-enhanced MR imaging misses 6%, while reasonably reducing the number of areas needing biopsy.
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Assessment of PI-RADS v2 for the Detection of Prostate Cancer

TL;DR: PI-RADS v2 improved diagnostic performance for the assessment of suspicious intraprostatic lesions identified in PI-R ADS v1 for both readers and led to higher inter-reader reliability.
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Dynamic contrast-enhanced magnetic resonance imaging and pharmacokinetic models in prostate cancer.

TL;DR: The potential clinical applications of DCE-MRI for prostate cancer include detection, localization, and staging, differentiation of recurrent cancer and estimation of the patient’s prognosis, as well as monitoring of treatment response.