T
Tommaso Casalini
Researcher at ETH Zurich
Publications - 49
Citations - 1080
Tommaso Casalini is an academic researcher from ETH Zurich. The author has contributed to research in topics: Self-healing hydrogels & Drug delivery. The author has an hindex of 15, co-authored 46 publications receiving 708 citations. Previous affiliations of Tommaso Casalini include SUPSI & Polytechnic University of Milan.
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A Perspective on Polylactic Acid-Based Polymers Use for Nanoparticles Synthesis and Applications.
TL;DR: A broad overview of PLA-based materials and their properties, which allow them gaining a leading role in the biomedical field is provided, and a specific focus on their recent use in nanomedicine is offered, highlighting opportunities and perspectives.
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Diffusion and Aggregation of Sodium Fluorescein in Aqueous Solutions
TL;DR: The results showed that dimerization does not occur in vacuo, as charge repulsion dominates, and that the minimum energy dimer structure is symmetric and stabilized by edge-to-face π-π interactions.
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Mathematical modeling of PLGA microparticles: from polymer degradation to drug release.
TL;DR: A mechanistic model describing the degradation of drug-loaded polylactic-co-glycolic acid microparticles and the drug release process from such devices is developed and validated, indicating that the model presented here, despite its simplicity, is able to describe the key phenomena governing the device behavior.
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Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation.
Hongji Yan,Tommaso Casalini,Gry Hulsart-Billström,Shujiang Wang,Oommen P. Oommen,Matteo Salvalaglio,Sune Larsson,Jöns Hilborn,Oommen P. Varghese +8 more
TL;DR: This study discovered a unique strategy to stabilize and sequester rhBMP-2 by enhancing its molecular interactions with hyaluronic acid (HA), an extracellular matrix (ECM) component by tuning the initial protonation state of carboxylic acid residues of HA in a covalently crosslinked hydrogel.
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Scaffolds as Structural Tools for Bone-Targeted Drug Delivery
Riccardo Ferracini,Isabel Martínez Herreros,Antonio Russo,Tommaso Casalini,Tommaso Casalini,Filippo Rossi,Giuseppe Perale +6 more
TL;DR: This review emphasizes recent progress in materials science that allows reliable scaffolds to be synthesized for targeted drug delivery in bone regeneration, also with respect to past directions no longer considered promising.