T
Tracy D. Wilkins
Researcher at Virginia Tech
Publications - 155
Citations - 9803
Tracy D. Wilkins is an academic researcher from Virginia Tech. The author has contributed to research in topics: Clostridium difficile & Clostridium difficile toxin A. The author has an hindex of 53, co-authored 155 publications receiving 9550 citations. Previous affiliations of Tracy D. Wilkins include American Red Cross.
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Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon.
TL;DR: The ability to utilize mucins and plant polysaccharides varied considerably among the Bacteroides species tested.
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Clostridium difficile: its disease and toxins.
TL;DR: There appears to be a cascade of events which result in the expression of the activity of these toxins, and these events, ranging from the recognition of a trisaccharide receptor by toxin A to the synergistic action of the toxins and their possible dissemination in the body, are discussed in this review.
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Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon.
TL;DR: Porcine gastric mucin, which was fermented by some strains of Ruminococcus torques and Bifidobacterium bifidum, was the only mucin utilized by any of the strains tested.
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Effects of Clostridium difficile toxins given intragastrically to animals.
TL;DR: The results suggest that toxins A and B act synergistically and that the action of toxin B may occur via the tissue damage caused by toxin A.
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Molecular characterization of the Clostridium difficile toxin A gene.
C H Dove,Shu-Zhen Wang,S B Price,Carol Phelps,David M. Lyerly,Tracy D. Wilkins,John L. Johnson +6 more
TL;DR: The gene encoding the toxin A protein of Clostridium difficile was cloned and sequenced, and the dipeptide tyrosine-phenylalanine was found in all 38 repeating units, and other amino acid sequences were unique to a specific class or subclass.