Tuomas Koivumäki

TL;DR: This study validated a previously determined optimized bioimpedance measurement configuration against traditional respiratory and cardiac measurement systems in 12 volunteers with high agreement and excellent correlations and has high potential to be adopted for dual-gating in clinical practice in the future.

TL;DR: Significant changes in the breast surface occur during the course of BC RT which should be considered in treatment planning and an additional margin outside the breastsurface of at least 8 mm is required to take into account the anatomical changes occurring during BC RT.

TL;DR: Residual variation was observed in the position of the heart in comparison to PTV, even with a visually guided DIBH technique, and these geometrical uncertainties should be taken into account when planning radiotherapy treatment.

TL;DR: In whole breast irradiation TD, E-VMAT and RA plans generated in this study achieved higher dose coverage and sparing of organs from the high dose in the vicinity of the PTV, achieving the lowest dose on contralateral organs.

TL;DR: This study shows the feasibility of bioimpedance measurements for dual gating in a clinical setting and enables simultaneous acquisition of respiratory and cardiac gating signals using a single device with standard ECG electrodes.