T
Tzong‐Shi Lu
Researcher at Brigham and Women's Hospital
Publications - 1
Citations - 34
Tzong‐Shi Lu is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Downregulation and upregulation & Angiotensin-converting enzyme 2. The author has an hindex of 1, co-authored 1 publications receiving 23 citations.
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Two hits to the renin-angiotensin system may play a key role in severe COVID-19.
TL;DR: It is hypothesize that two hits to the RAS drives COVID‐19 progression and the first hit originates from chronic inflammation activating the ACE/Ang II/AT1R axis, and the second originated from the CO VID‐19 infection inactivating the ACE2/Ang (1‐7)/Mas axis.